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Nutrition in pancreatic diseases.
Best Pract Res Clin Gastroenterol. 2006; 20(3):507-29.BP

Abstract

The pancreas plays a major role in nutrient digestion. Therefore, in both acute and chronic pancreatitis, exocrine and endocrine pancreatic insufficiency can develop, impairing digestive and absorptive processes. These changes can lead to malnutrition over time. In parallel to these changes, decreased caloric intake and increased metabolic activity are often present. Nutritional deficiencies negatively affect outcome if they are not treated. Nutritional assessment and the clinical severity of the disease are important for planning any nutritional intervention. In severe acute pancreatitis, enteral nutrition with a naso-jejunal feeding tube and a low molecular diet displays clear advantages compared to parenteral nutrition. Infectious complications, length of hospital stay and the need for surgery are reduced. Furthermore, enteral nutrition is less costly than parenteral nutrition. Parenteral nutrition is reserved for patients who do not tolerate enteral nutrition. Abstinence from alcohol, dietary modifications and pancreatic enzyme supplementation is sufficient in over 80% of patients with chronic pancreatitis. In addition, oral supplements are helpful. Enteral nutrition can be necessary if weight loss continues. Parenteral nutrition is very seldom used in patients with chronic pancreatitis.

Authors+Show Affiliations

GI-Unit, University Hospital Liestal, Kantonsspital Liestal, CH-4410 Liestal, Switzerland. remy.meier@ksli.chNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16782526

Citation

Meier, Rémy F., and Christoph Beglinger. "Nutrition in Pancreatic Diseases." Best Practice & Research. Clinical Gastroenterology, vol. 20, no. 3, 2006, pp. 507-29.
Meier RF, Beglinger C. Nutrition in pancreatic diseases. Best Pract Res Clin Gastroenterol. 2006;20(3):507-29.
Meier, R. F., & Beglinger, C. (2006). Nutrition in pancreatic diseases. Best Practice & Research. Clinical Gastroenterology, 20(3), 507-29.
Meier RF, Beglinger C. Nutrition in Pancreatic Diseases. Best Pract Res Clin Gastroenterol. 2006;20(3):507-29. PubMed PMID: 16782526.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutrition in pancreatic diseases. AU - Meier,Rémy F, AU - Beglinger,Christoph, PY - 2006/6/20/pubmed PY - 2006/9/29/medline PY - 2006/6/20/entrez SP - 507 EP - 29 JF - Best practice & research. Clinical gastroenterology JO - Best Pract Res Clin Gastroenterol VL - 20 IS - 3 N2 - The pancreas plays a major role in nutrient digestion. Therefore, in both acute and chronic pancreatitis, exocrine and endocrine pancreatic insufficiency can develop, impairing digestive and absorptive processes. These changes can lead to malnutrition over time. In parallel to these changes, decreased caloric intake and increased metabolic activity are often present. Nutritional deficiencies negatively affect outcome if they are not treated. Nutritional assessment and the clinical severity of the disease are important for planning any nutritional intervention. In severe acute pancreatitis, enteral nutrition with a naso-jejunal feeding tube and a low molecular diet displays clear advantages compared to parenteral nutrition. Infectious complications, length of hospital stay and the need for surgery are reduced. Furthermore, enteral nutrition is less costly than parenteral nutrition. Parenteral nutrition is reserved for patients who do not tolerate enteral nutrition. Abstinence from alcohol, dietary modifications and pancreatic enzyme supplementation is sufficient in over 80% of patients with chronic pancreatitis. In addition, oral supplements are helpful. Enteral nutrition can be necessary if weight loss continues. Parenteral nutrition is very seldom used in patients with chronic pancreatitis. SN - 1521-6918 UR - https://www.unboundmedicine.com/medline/citation/16782526/Nutrition_in_pancreatic_diseases_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1521-6918(06)00007-2 DB - PRIME DP - Unbound Medicine ER -