Tags

Type your tag names separated by a space and hit enter

Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of intraductal papillary mucinous neoplasm of the pancreas is highly predictive of pancreatic neoplasia.
Diagn Cytopathol. 2006 Jul; 34(7):457-62.DC

Abstract

Intraductal papillary mucinous neoplasms (IPMN) have been considered difficult to diagnose by fine-needle aspiration (FNA) cytology. We identified 57 cases diagnosed as IPMN or consistent with IPMN by endoscopic ultrasound (EUS)-guided FNA over a 9-yr period. Histologic follow-up was available for 20 patients (35%). Pancreatic neoplasia was demonstrated in 18 of these cases (90%). The histologic diagnoses were IPMN (16 cases), pancreatic intraductal neoplasia (grade 1b, 1 case), invasive mucin-producing adenocarcinoma (1 case), and chronic pancreatitis with a pseudocyst (2 cases). Sixty-two cases of IPMN without coexisting adenocarcinoma were diagnosed by histology during this time period. Of these, 35 (56%) had a preceding EUS-guided FNA. The diagnosis made by EUS-guided FNA in these 35 cases was negative or nondiagnostic (6 cases), benign cyst (1 case), chronic pancreatitis (2 cases), atypical ductal cells (2 cases), adenocarcinoma or suspicious for adenocarcinoma (3 cases), consistent with mucinous cystic neoplasm (4 cases), and IPMN or consistent with IPMN (16 cases). An EUS FNA diagnosis of probable or definite neoplasia was, therefore, made in 71% of cases of histologically proven IPMN.

Authors+Show Affiliations

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202-5280, USA. reemerso@iupui.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

16783773

Citation

Emerson, Robert E., et al. "Endoscopic Ultrasound-guided Fine-needle Aspiration Cytology Diagnosis of Intraductal Papillary Mucinous Neoplasm of the Pancreas Is Highly Predictive of Pancreatic Neoplasia." Diagnostic Cytopathology, vol. 34, no. 7, 2006, pp. 457-62.
Emerson RE, Randolph ML, Cramer HM. Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of intraductal papillary mucinous neoplasm of the pancreas is highly predictive of pancreatic neoplasia. Diagn Cytopathol. 2006;34(7):457-62.
Emerson, R. E., Randolph, M. L., & Cramer, H. M. (2006). Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of intraductal papillary mucinous neoplasm of the pancreas is highly predictive of pancreatic neoplasia. Diagnostic Cytopathology, 34(7), 457-62.
Emerson RE, Randolph ML, Cramer HM. Endoscopic Ultrasound-guided Fine-needle Aspiration Cytology Diagnosis of Intraductal Papillary Mucinous Neoplasm of the Pancreas Is Highly Predictive of Pancreatic Neoplasia. Diagn Cytopathol. 2006;34(7):457-62. PubMed PMID: 16783773.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of intraductal papillary mucinous neoplasm of the pancreas is highly predictive of pancreatic neoplasia. AU - Emerson,Robert E, AU - Randolph,Melissa L, AU - Cramer,Harvey M, PY - 2006/6/20/pubmed PY - 2006/8/25/medline PY - 2006/6/20/entrez SP - 457 EP - 62 JF - Diagnostic cytopathology JO - Diagn Cytopathol VL - 34 IS - 7 N2 - Intraductal papillary mucinous neoplasms (IPMN) have been considered difficult to diagnose by fine-needle aspiration (FNA) cytology. We identified 57 cases diagnosed as IPMN or consistent with IPMN by endoscopic ultrasound (EUS)-guided FNA over a 9-yr period. Histologic follow-up was available for 20 patients (35%). Pancreatic neoplasia was demonstrated in 18 of these cases (90%). The histologic diagnoses were IPMN (16 cases), pancreatic intraductal neoplasia (grade 1b, 1 case), invasive mucin-producing adenocarcinoma (1 case), and chronic pancreatitis with a pseudocyst (2 cases). Sixty-two cases of IPMN without coexisting adenocarcinoma were diagnosed by histology during this time period. Of these, 35 (56%) had a preceding EUS-guided FNA. The diagnosis made by EUS-guided FNA in these 35 cases was negative or nondiagnostic (6 cases), benign cyst (1 case), chronic pancreatitis (2 cases), atypical ductal cells (2 cases), adenocarcinoma or suspicious for adenocarcinoma (3 cases), consistent with mucinous cystic neoplasm (4 cases), and IPMN or consistent with IPMN (16 cases). An EUS FNA diagnosis of probable or definite neoplasia was, therefore, made in 71% of cases of histologically proven IPMN. SN - 8755-1039 UR - https://www.unboundmedicine.com/medline/citation/16783773/Endoscopic_ultrasound_guided_fine_needle_aspiration_cytology_diagnosis_of_intraductal_papillary_mucinous_neoplasm_of_the_pancreas_is_highly_predictive_of_pancreatic_neoplasia_ L2 - https://doi.org/10.1002/dc.20446 DB - PRIME DP - Unbound Medicine ER -