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[The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus].
Rev Med Suisse. 2006 May 31; 2(68):1480-2, 1484-5.RM

Abstract

The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus The concept of "Polypill" was developed from modeling analyses and the data were extracted from randomized-control trials and epidemiological studies. This "Polypill" should be a combination of three antihypertensive drugs associated to aspirin, a statin and folic acid. This "Polypill" would allow to reduce of more than 80% the cardiovascular events. The original publication suggests that all subjects of more than 55 years could benefit from this magic pill. Numerous positive and negative reactions showed themselves further to this publication. Other approaches based on the change of lifestyle seem so effective. Nevertheless, to have a really effective approach the therapeutic educational dimension should be also included in the basic strategy.

Authors+Show Affiliations

Ruiz J
Service d'endocrinologie, diabétologie et métabolisme CHUV, 101 Lausanne. Juan.Ruiz@chuv.ch
Egli M
No affiliation info available

MeSH

Antihypertensive AgentsAspirinCardiovascular DiseasesDiabetes Mellitus, Type 2Drug CombinationsFolic AcidHumansHydroxymethylglutaryl-CoA Reductase InhibitorsPlatelet Aggregation Inhibitors

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

16783994

Citation

Ruiz, J, and M Egli. "[The Polypill: Between Myths and Reality in the Treatment of Type 2 Diabetes Mellitus]." Revue Medicale Suisse, vol. 2, no. 68, 2006, pp. 1480-2, 1484-5.
Ruiz J, Egli M. [The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus]. Rev Med Suisse. 2006;2(68):1480-2, 1484-5.
Ruiz, J., & Egli, M. (2006). [The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus]. Revue Medicale Suisse, 2(68), 1480-2, 1484-5.
Ruiz J, Egli M. [The Polypill: Between Myths and Reality in the Treatment of Type 2 Diabetes Mellitus]. Rev Med Suisse. 2006 May 31;2(68):1480-2, 1484-5. PubMed PMID: 16783994.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus]. AU - Ruiz,J, AU - Egli,M, PY - 2006/6/21/pubmed PY - 2006/8/3/medline PY - 2006/6/21/entrez SP - 1480-2, 1484-5 JF - Revue medicale suisse JO - Rev Med Suisse VL - 2 IS - 68 N2 - The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus The concept of "Polypill" was developed from modeling analyses and the data were extracted from randomized-control trials and epidemiological studies. This "Polypill" should be a combination of three antihypertensive drugs associated to aspirin, a statin and folic acid. This "Polypill" would allow to reduce of more than 80% the cardiovascular events. The original publication suggests that all subjects of more than 55 years could benefit from this magic pill. Numerous positive and negative reactions showed themselves further to this publication. Other approaches based on the change of lifestyle seem so effective. Nevertheless, to have a really effective approach the therapeutic educational dimension should be also included in the basic strategy. SN - 1660-9379 UR - https://www.unboundmedicine.com/medline/citation/16783994/[The_Polypill:_between_myths_and_reality_in_the_treatment_of_type_2_diabetes_mellitus]_ DB - PRIME DP - Unbound Medicine ER -