Tags

Type your tag names separated by a space and hit enter

Acanthamoeba keratitis and contact lens disinfecting solutions.
Ophthalmologica. 2006; 220(4):238-41.O

Abstract

OBJECTIVES

To report cases of culture-proved Acanthamoeba keratitis in Greece over a 10-year period and to evaluate the effectiveness of the commonly used commercial contact lens disinfecting systems in clinical cases of Acanthamoeba keratitis.

MATERIAL AND METHODS

During the years 1994-2004, 45 contact lens wearers and 3 non-contact lens wearers presenting with symptoms and signs of keratitis underwent corneal sampling. The scrapings obtained were inoculated directly onto appropriate culture media for bacteria, fungi and Acanthamoeba. All proved positive for Acanthamoeba. The contact lenses and contact lens disinfecting solutions (16 one-step 3% hydrogen peroxide and 3 multipurpose solutions) of 19/45 patients with culture-proven Acanthamoeba keratitis were cultured for bacteria, fungi and Acanthamoeba.

RESULTS

Acanthamoeba was isolated from contact lenses and contact lens disinfecting solutions in all 19 cases of Acanthamoeba keratitis studied.

CONCLUSIONS

The main risk factor for corneal infection in contact lens wearers is the use of contact lens disinfecting systems ineffective at killing Acanthamoeba cysts and trophozoites, as well as bacteria and fungi. Improvement or development of new contact lens disinfecting systems by manufacturers is needed to prevent Acanthamoeba keratitis.

Authors+Show Affiliations

Microbiology Laboratory, General Hospital of Athens 'G. Gennimatas', Athens, Greece. ktzane@otenet.grNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16785754

Citation

Tzanetou, K, et al. "Acanthamoeba Keratitis and Contact Lens Disinfecting Solutions." Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde, vol. 220, no. 4, 2006, pp. 238-41.
Tzanetou K, Miltsakakis D, Droutsas D, et al. Acanthamoeba keratitis and contact lens disinfecting solutions. Ophthalmologica. 2006;220(4):238-41.
Tzanetou, K., Miltsakakis, D., Droutsas, D., Alimisi, S., Petropoulou, D., Ganteris, G., Dolapsaki, E., Markomichelakis, N., Mallias, I., & Malamou-Lada, E. (2006). Acanthamoeba keratitis and contact lens disinfecting solutions. Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde, 220(4), 238-41.
Tzanetou K, et al. Acanthamoeba Keratitis and Contact Lens Disinfecting Solutions. Ophthalmologica. 2006;220(4):238-41. PubMed PMID: 16785754.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acanthamoeba keratitis and contact lens disinfecting solutions. AU - Tzanetou,K, AU - Miltsakakis,D, AU - Droutsas,D, AU - Alimisi,S, AU - Petropoulou,D, AU - Ganteris,G, AU - Dolapsaki,E, AU - Markomichelakis,N, AU - Mallias,I, AU - Malamou-Lada,E, PY - 2005/11/11/received PY - 2005/11/25/accepted PY - 2006/6/21/pubmed PY - 2006/8/2/medline PY - 2006/6/21/entrez SP - 238 EP - 41 JF - Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde JO - Ophthalmologica VL - 220 IS - 4 N2 - OBJECTIVES: To report cases of culture-proved Acanthamoeba keratitis in Greece over a 10-year period and to evaluate the effectiveness of the commonly used commercial contact lens disinfecting systems in clinical cases of Acanthamoeba keratitis. MATERIAL AND METHODS: During the years 1994-2004, 45 contact lens wearers and 3 non-contact lens wearers presenting with symptoms and signs of keratitis underwent corneal sampling. The scrapings obtained were inoculated directly onto appropriate culture media for bacteria, fungi and Acanthamoeba. All proved positive for Acanthamoeba. The contact lenses and contact lens disinfecting solutions (16 one-step 3% hydrogen peroxide and 3 multipurpose solutions) of 19/45 patients with culture-proven Acanthamoeba keratitis were cultured for bacteria, fungi and Acanthamoeba. RESULTS: Acanthamoeba was isolated from contact lenses and contact lens disinfecting solutions in all 19 cases of Acanthamoeba keratitis studied. CONCLUSIONS: The main risk factor for corneal infection in contact lens wearers is the use of contact lens disinfecting systems ineffective at killing Acanthamoeba cysts and trophozoites, as well as bacteria and fungi. Improvement or development of new contact lens disinfecting systems by manufacturers is needed to prevent Acanthamoeba keratitis. SN - 0030-3755 UR - https://www.unboundmedicine.com/medline/citation/16785754/Acanthamoeba_keratitis_and_contact_lens_disinfecting_solutions_ L2 - https://www.karger.com?DOI=10.1159/000093077 DB - PRIME DP - Unbound Medicine ER -