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Thymic stromal lymphopoietin in normal and pathogenic T cell development and function.
Nat Immunol. 2006 Jul; 7(7):709-14.NI

Abstract

Thymic stromal lymphopoietin, a four helix-bundle cytokine, is expressed mainly by barrier epithelial cells and is a potent activator of several cell types, particularly myeloid dendritic cells. TSLP influences the outcome of interactions between dendritic cells and CD4+ thymocytes and T cells in many situations, such as the regulation of the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and induction of CD4+ T cell-mediated allergic inflammation.

Authors+Show Affiliations

Immunology Program, Benaroya Research Institute, Seattle, Washington 98101, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

16785889

Citation

Ziegler, Steven F., and Yong-Jun Liu. "Thymic Stromal Lymphopoietin in Normal and Pathogenic T Cell Development and Function." Nature Immunology, vol. 7, no. 7, 2006, pp. 709-14.
Ziegler SF, Liu YJ. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol. 2006;7(7):709-14.
Ziegler, S. F., & Liu, Y. J. (2006). Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nature Immunology, 7(7), 709-14.
Ziegler SF, Liu YJ. Thymic Stromal Lymphopoietin in Normal and Pathogenic T Cell Development and Function. Nat Immunol. 2006;7(7):709-14. PubMed PMID: 16785889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. AU - Ziegler,Steven F, AU - Liu,Yong-Jun, PY - 2006/02/09/received PY - 2006/04/21/accepted PY - 2006/6/21/pubmed PY - 2006/9/20/medline PY - 2006/6/21/entrez SP - 709 EP - 14 JF - Nature immunology JO - Nat Immunol VL - 7 IS - 7 N2 - Thymic stromal lymphopoietin, a four helix-bundle cytokine, is expressed mainly by barrier epithelial cells and is a potent activator of several cell types, particularly myeloid dendritic cells. TSLP influences the outcome of interactions between dendritic cells and CD4+ thymocytes and T cells in many situations, such as the regulation of the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and induction of CD4+ T cell-mediated allergic inflammation. SN - 1529-2908 UR - https://www.unboundmedicine.com/medline/citation/16785889/Thymic_stromal_lymphopoietin_in_normal_and_pathogenic_T_cell_development_and_function_ L2 - https://doi.org/10.1038/ni1360 DB - PRIME DP - Unbound Medicine ER -