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Cord blood leptin levels in Pakistani newborns: relationship with birth weight, length and occipitofrontal circumference.
J Coll Physicians Surg Pak. 2006 Jun; 16(6):393-5.JC

Abstract

OBJECTIVE

To determine the serum leptin levels in cord blood of Pakistani newborns and to ascertain the relationship between serum leptin and anthropometric parameters i.e. birth weight, length and OFC.

STUDY DESIGN

A cross-sectional study.

PLACE AND DURATION

Lady Dufferin Hospital and Ziauddin Hospital, Karachi from 1999 to 2000.

PATIENTS AND METHODS

Leptin concentration was measured in 110 newborns of mothers of normal antenatal history from venous cord blood, using Active Elisa Kit (DSL-10-23100). Samples were selected according to availability.

RESULTS

Mean birth weight, length and occipitofrontal circumference (OFC) were 3.0+/-0.4 kg, 48.7+/-2.3 cms and 33.1+/-0.8 cms, respectively. Mean serum leptin levels was 10.0+/-7.5 ng/ml. Serum leptin levels were found to be positively correlated with birth weight (r=0.16, p=0.04), and OFC (r=0.33, p<0.01), whereas no significant relationship was found with length of the babies.

CONCLUSION

The reported results suggest that leptin may play role in newborns body weight and energy expenditure as in adults and children.

Authors+Show Affiliations

Department of Physiology, Liaquat College of Medicine and Dentistry, Karachi, Pakistan, and Khams Civil Hospital, King Khalid University Abha, Kingdom of Saudi Arabia. ghulam.lakho@aku.edu [corrected]No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16787614

Citation

Lakho, Ghulam Rehmani, et al. "Cord Blood Leptin Levels in Pakistani Newborns: Relationship With Birth Weight, Length and Occipitofrontal Circumference." Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, vol. 16, no. 6, 2006, pp. 393-5.
Lakho GR, Haq Z, Chundrigar T, et al. Cord blood leptin levels in Pakistani newborns: relationship with birth weight, length and occipitofrontal circumference. J Coll Physicians Surg Pak. 2006;16(6):393-5.
Lakho, G. R., Haq, Z., Chundrigar, T., Nazir, K., & Qureshi, M. A. (2006). Cord blood leptin levels in Pakistani newborns: relationship with birth weight, length and occipitofrontal circumference. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 16(6), 393-5.
Lakho GR, et al. Cord Blood Leptin Levels in Pakistani Newborns: Relationship With Birth Weight, Length and Occipitofrontal Circumference. J Coll Physicians Surg Pak. 2006;16(6):393-5. PubMed PMID: 16787614.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cord blood leptin levels in Pakistani newborns: relationship with birth weight, length and occipitofrontal circumference. AU - Lakho,Ghulam Rehmani, AU - Haq,Zeba, AU - Chundrigar,Tariq, AU - Nazir,Kauser, AU - Qureshi,Masood Anwar, PY - 2005/05/04/received PY - 2006/05/09/accepted PY - 2006/6/22/pubmed PY - 2006/10/7/medline PY - 2006/6/22/entrez SP - 393 EP - 5 JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP JO - J Coll Physicians Surg Pak VL - 16 IS - 6 N2 - OBJECTIVE: To determine the serum leptin levels in cord blood of Pakistani newborns and to ascertain the relationship between serum leptin and anthropometric parameters i.e. birth weight, length and OFC. STUDY DESIGN: A cross-sectional study. PLACE AND DURATION: Lady Dufferin Hospital and Ziauddin Hospital, Karachi from 1999 to 2000. PATIENTS AND METHODS: Leptin concentration was measured in 110 newborns of mothers of normal antenatal history from venous cord blood, using Active Elisa Kit (DSL-10-23100). Samples were selected according to availability. RESULTS: Mean birth weight, length and occipitofrontal circumference (OFC) were 3.0+/-0.4 kg, 48.7+/-2.3 cms and 33.1+/-0.8 cms, respectively. Mean serum leptin levels was 10.0+/-7.5 ng/ml. Serum leptin levels were found to be positively correlated with birth weight (r=0.16, p=0.04), and OFC (r=0.33, p<0.01), whereas no significant relationship was found with length of the babies. CONCLUSION: The reported results suggest that leptin may play role in newborns body weight and energy expenditure as in adults and children. SN - 1022-386X UR - https://www.unboundmedicine.com/medline/citation/16787614/Cord_blood_leptin_levels_in_Pakistani_newborns:_relationship_with_birth_weight_length_and_occipitofrontal_circumference_ L2 - https://medlineplus.gov/birthweight.html DB - PRIME DP - Unbound Medicine ER -