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Supplementation of fish-oil and soy-oil during pregnancy and psychomotor development of infants.
J Health Popul Nutr. 2006 Mar; 24(1):48-56.JH

Abstract

Supplementation of docosahexaenoic acid (DHA) in infancy improves neuro-developmental outcomes, but there is limited information about the impact of supplementing pregnant mothers with DHA on the development of their infants. In a follow-up of a randomized, double-blind controlled trial with 400 pregnant mothers, the effects of supplementation of fish-oil or soy-oil (4 g/day) during the last trimester of pregnancy on psychomotor development and behaviour of infants at 10 months of age (n=249) were assessed. The quality of psychosocial stimulation at home (HOME) and nutritional status of the subjects were also measured. There were no significant differences in the fish-oil group and soy-oil group in any of the developmental (mean +/-SD mental development index: 102.5 +/- 8.0 vs. 101.5 +/- 7.8, psychomotor development index: 101.7 +/- 10.0 vs. 100.5 +/- 10.1) or behavioural outcomes. It may, therefore, be concluded that supplementation of fish-oil during the last trimester of pregnancy does not have any added benefit over supplementation of soy-oil on the development or behaviour of infants in this population.

Authors+Show Affiliations

Clinical Sciences Division, ICDDR,B: Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh. ftofail@icddrb.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16796150

Citation

Tofail, Fahmida, et al. "Supplementation of Fish-oil and Soy-oil During Pregnancy and Psychomotor Development of Infants." Journal of Health, Population, and Nutrition, vol. 24, no. 1, 2006, pp. 48-56.
Tofail F, Kabir I, Hamadani JD, et al. Supplementation of fish-oil and soy-oil during pregnancy and psychomotor development of infants. J Health Popul Nutr. 2006;24(1):48-56.
Tofail, F., Kabir, I., Hamadani, J. D., Chowdhury, F., Yesmin, S., Mehreen, F., & Huda, S. N. (2006). Supplementation of fish-oil and soy-oil during pregnancy and psychomotor development of infants. Journal of Health, Population, and Nutrition, 24(1), 48-56.
Tofail F, et al. Supplementation of Fish-oil and Soy-oil During Pregnancy and Psychomotor Development of Infants. J Health Popul Nutr. 2006;24(1):48-56. PubMed PMID: 16796150.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Supplementation of fish-oil and soy-oil during pregnancy and psychomotor development of infants. AU - Tofail,Fahmida, AU - Kabir,Iqbal, AU - Hamadani,Jena D, AU - Chowdhury,Fahima, AU - Yesmin,Sakila, AU - Mehreen,Fardina, AU - Huda,Syed N, PY - 2006/6/27/pubmed PY - 2006/7/25/medline PY - 2006/6/27/entrez SP - 48 EP - 56 JF - Journal of health, population, and nutrition JO - J Health Popul Nutr VL - 24 IS - 1 N2 - Supplementation of docosahexaenoic acid (DHA) in infancy improves neuro-developmental outcomes, but there is limited information about the impact of supplementing pregnant mothers with DHA on the development of their infants. In a follow-up of a randomized, double-blind controlled trial with 400 pregnant mothers, the effects of supplementation of fish-oil or soy-oil (4 g/day) during the last trimester of pregnancy on psychomotor development and behaviour of infants at 10 months of age (n=249) were assessed. The quality of psychosocial stimulation at home (HOME) and nutritional status of the subjects were also measured. There were no significant differences in the fish-oil group and soy-oil group in any of the developmental (mean +/-SD mental development index: 102.5 +/- 8.0 vs. 101.5 +/- 7.8, psychomotor development index: 101.7 +/- 10.0 vs. 100.5 +/- 10.1) or behavioural outcomes. It may, therefore, be concluded that supplementation of fish-oil during the last trimester of pregnancy does not have any added benefit over supplementation of soy-oil on the development or behaviour of infants in this population. SN - 1606-0997 UR - https://www.unboundmedicine.com/medline/citation/16796150/Supplementation_of_fish_oil_and_soy_oil_during_pregnancy_and_psychomotor_development_of_infants_ L2 - https://ClinicalTrials.gov/search/term=16796150 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -