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Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou.
Invest Ophthalmol Vis Sci. 2006 Jul; 47(7):2782-8.IO

Abstract

PURPOSE

To assess the prevalence and mechanism of glaucoma in adults living in an urban area of southern China.

METHODS

Random clustering sampling was used to identify adults aged 50 years and over in Liwan District, Guangzhou. Glaucoma was diagnosed with the ISGEO (International Society of Geographical and Epidemiological Ophthalmology) classification scheme. All subjects underwent gonioscopy.

RESULTS

In the study, 1504 subjects (75.3% participation rate) were examined, with a crude prevalence of all glaucoma of 3.8% (95% confidence interval [CI], 2.8%-4.8%). Primary open-angle glaucoma (POAG) was found in 2.1% (95% CI, 1.4%-2.8%) and primary angle-closure glaucoma (PACG) in 1.5% (95% CI, 0.8%-2.1%). The prevalence of all glaucoma was significantly higher in older people and men.

CONCLUSIONS

POAG was more common than PACG in this southern Chinese population, with rates similar to those reported in Chinese Singaporeans. The age-adjusted rate of POAG was similar to that found in European-derived populations, but PACG was more common among Chinese, indicating that there is a large burden of glaucoma in the Chinese people.

Authors+Show Affiliations

Institute of Ophthalmology, University College London, and Glaucoma Research Unit, Moorfields Eye Hospital, United Kingdom. mingguang_he@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16799014

Citation

He, Mingguang, et al. "Prevalence and Clinical Characteristics of Glaucoma in Adult Chinese: a Population-based Study in Liwan District, Guangzhou." Investigative Ophthalmology & Visual Science, vol. 47, no. 7, 2006, pp. 2782-8.
He M, Foster PJ, Ge J, et al. Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou. Invest Ophthalmol Vis Sci. 2006;47(7):2782-8.
He, M., Foster, P. J., Ge, J., Huang, W., Zheng, Y., Friedman, D. S., Lee, P. S., & Khaw, P. T. (2006). Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou. Investigative Ophthalmology & Visual Science, 47(7), 2782-8.
He M, et al. Prevalence and Clinical Characteristics of Glaucoma in Adult Chinese: a Population-based Study in Liwan District, Guangzhou. Invest Ophthalmol Vis Sci. 2006;47(7):2782-8. PubMed PMID: 16799014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou. AU - He,Mingguang, AU - Foster,Paul J, AU - Ge,Jian, AU - Huang,Wenyong, AU - Zheng,Yingfeng, AU - Friedman,David S, AU - Lee,Pak Sang, AU - Khaw,Peng T, PY - 2006/6/27/pubmed PY - 2006/8/8/medline PY - 2006/6/27/entrez SP - 2782 EP - 8 JF - Investigative ophthalmology & visual science JO - Invest. Ophthalmol. Vis. Sci. VL - 47 IS - 7 N2 - PURPOSE: To assess the prevalence and mechanism of glaucoma in adults living in an urban area of southern China. METHODS: Random clustering sampling was used to identify adults aged 50 years and over in Liwan District, Guangzhou. Glaucoma was diagnosed with the ISGEO (International Society of Geographical and Epidemiological Ophthalmology) classification scheme. All subjects underwent gonioscopy. RESULTS: In the study, 1504 subjects (75.3% participation rate) were examined, with a crude prevalence of all glaucoma of 3.8% (95% confidence interval [CI], 2.8%-4.8%). Primary open-angle glaucoma (POAG) was found in 2.1% (95% CI, 1.4%-2.8%) and primary angle-closure glaucoma (PACG) in 1.5% (95% CI, 0.8%-2.1%). The prevalence of all glaucoma was significantly higher in older people and men. CONCLUSIONS: POAG was more common than PACG in this southern Chinese population, with rates similar to those reported in Chinese Singaporeans. The age-adjusted rate of POAG was similar to that found in European-derived populations, but PACG was more common among Chinese, indicating that there is a large burden of glaucoma in the Chinese people. SN - 0146-0404 UR - https://www.unboundmedicine.com/medline/citation/16799014/Prevalence_and_clinical_characteristics_of_glaucoma_in_adult_Chinese:_a_population_based_study_in_Liwan_District_Guangzhou_ L2 - http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.06-0051 DB - PRIME DP - Unbound Medicine ER -