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Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices.
World J Gastroenterol. 2006 Jun 28; 12(24):3866-73.WJ

Abstract

AIM

To evaluate the effect of three interventional treatments involving transvenous obliteration for the treatment of gastric varices, and to compare the efficacy and adverse effects of these methods.

METHODS

From 1995 to 2004, 93 patients with gastric fundal varices underwent interventional radiologic embolotherapy at our hospital. Of the 93 patients, 75 were treated with the balloon-occluded retrograde transvenous obliteration (BRTO) procedure; 8 were with the percutaneous transhepatic obliteration (PTO) procedure; and 10 were with the combined BRTO and PTO therapy. A follow-up evaluation examined the rates of survival, recurrence and rebleeding of the gastric varices, worsening of esophageal varices and complications in each group.

RESULTS

The BRTO, PTO, and combined therapy were technically successful in 81% (75/93), 44% (8/18), and 100% (10/10) patients, respectively. Recurrence of gastric varices was found in 3 patients in the BRTO group and in 3 patients in the PTO group. Rebleeding was observed in 1 patient in the BRTO group and in 1 patient in the PTO group. The 1- and 3-year survival rates were 98% and 87% in the patients without hepatocellular carcinoma (HCC) in the BRTO group, 100% and 100% in the PTO group, and 90% and 75% in the combined therapy group, respectively.

CONCLUSION

Combined BRTO and PTO therapy may rescue cases with uncontrollable gastric fundal varices that remained even after treatment with BRTO and/or PTO, though there were limitations of our study, including retrospective nature and discrepancy in sample size between the BRTO, PTO and combined therapy groups.

Authors+Show Affiliations

Department of Gastroenterology, Maebashi Red Cross Hospital, Japan. h-arai0213@jcom.home.ne.jpNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

16804972

Citation

Arai, Hirotaka, et al. "Efficacy of Balloon-occluded Retrograde Transvenous Obliteration, Percutaneous Transhepatic Obliteration and Combined Techniques for the Management of Gastric Fundal Varices." World Journal of Gastroenterology, vol. 12, no. 24, 2006, pp. 3866-73.
Arai H, Abe T, Takagi H, et al. Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices. World J Gastroenterol. 2006;12(24):3866-73.
Arai, H., Abe, T., Takagi, H., & Mori, M. (2006). Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices. World Journal of Gastroenterology, 12(24), 3866-73.
Arai H, et al. Efficacy of Balloon-occluded Retrograde Transvenous Obliteration, Percutaneous Transhepatic Obliteration and Combined Techniques for the Management of Gastric Fundal Varices. World J Gastroenterol. 2006 Jun 28;12(24):3866-73. PubMed PMID: 16804972.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices. AU - Arai,Hirotaka, AU - Abe,Takehiko, AU - Takagi,Hitoshi, AU - Mori,Masatomo, PY - 2006/6/29/pubmed PY - 2006/8/23/medline PY - 2006/6/29/entrez SP - 3866 EP - 73 JF - World journal of gastroenterology JO - World J Gastroenterol VL - 12 IS - 24 N2 - AIM: To evaluate the effect of three interventional treatments involving transvenous obliteration for the treatment of gastric varices, and to compare the efficacy and adverse effects of these methods. METHODS: From 1995 to 2004, 93 patients with gastric fundal varices underwent interventional radiologic embolotherapy at our hospital. Of the 93 patients, 75 were treated with the balloon-occluded retrograde transvenous obliteration (BRTO) procedure; 8 were with the percutaneous transhepatic obliteration (PTO) procedure; and 10 were with the combined BRTO and PTO therapy. A follow-up evaluation examined the rates of survival, recurrence and rebleeding of the gastric varices, worsening of esophageal varices and complications in each group. RESULTS: The BRTO, PTO, and combined therapy were technically successful in 81% (75/93), 44% (8/18), and 100% (10/10) patients, respectively. Recurrence of gastric varices was found in 3 patients in the BRTO group and in 3 patients in the PTO group. Rebleeding was observed in 1 patient in the BRTO group and in 1 patient in the PTO group. The 1- and 3-year survival rates were 98% and 87% in the patients without hepatocellular carcinoma (HCC) in the BRTO group, 100% and 100% in the PTO group, and 90% and 75% in the combined therapy group, respectively. CONCLUSION: Combined BRTO and PTO therapy may rescue cases with uncontrollable gastric fundal varices that remained even after treatment with BRTO and/or PTO, though there were limitations of our study, including retrospective nature and discrepancy in sample size between the BRTO, PTO and combined therapy groups. SN - 1007-9327 UR - https://www.unboundmedicine.com/medline/citation/16804972/Efficacy_of_balloon_occluded_retrograde_transvenous_obliteration_percutaneous_transhepatic_obliteration_and_combined_techniques_for_the_management_of_gastric_fundal_varices_ L2 - https://www.wjgnet.com/1007-9327/full/v12/i24/3866.htm DB - PRIME DP - Unbound Medicine ER -