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Antioxidant properties of methanolic extracts from leaves of Rhazya stricta.
J Med Food. 2006 Summer; 9(2):270-5.JM

Abstract

Because of increased safety concerns about synthetic antioxidants, exploitation of cheaper and safer sources of antioxidants based on natural origin is the focus of research nowadays. Rhazya stricta is a medicinally important plant native to South Asia. Extraction of antioxidants was carried out in different solvent systems, i.e., water, 80% methanol, 70% ethanol, and diethyl ether. The methanolic extract exhibited the highest total phenolic content among the extracts; therefore for further studies the methanolic extract was employed. Antioxidant activity measurement in the linoleic acid system, metal chelating activity, reducing power, scavenging effect on 1,1-diphenyl-2-picrylhydrazyl free radical, and superoxide anion radical scavenging activity were taken as the parameters for assessment of antioxidant potential of methanolic extracts. Results were compared with alpha-tocopherol and the synthetic antioxidant butylated hydroxyanisole. The antioxidant potential of methanolic extracts of R. stricta leaves was comparable with previously exploited potent antioxidants and is strongly concentration dependent.

Authors+Show Affiliations

Departments of Chemistry , University of Sargodha, Sargodha, Pakistan. ranashahid313@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16822215

Citation

Iqbal, Shahid, et al. "Antioxidant Properties of Methanolic Extracts From Leaves of Rhazya Stricta." Journal of Medicinal Food, vol. 9, no. 2, 2006, pp. 270-5.
Iqbal S, Bhanger MI, Akhtar M, et al. Antioxidant properties of methanolic extracts from leaves of Rhazya stricta. J Med Food. 2006;9(2):270-5.
Iqbal, S., Bhanger, M. I., Akhtar, M., Anwar, F., Ahmed, K. R., & Anwer, T. (2006). Antioxidant properties of methanolic extracts from leaves of Rhazya stricta. Journal of Medicinal Food, 9(2), 270-5.
Iqbal S, et al. Antioxidant Properties of Methanolic Extracts From Leaves of Rhazya Stricta. J Med Food. 2006;9(2):270-5. PubMed PMID: 16822215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant properties of methanolic extracts from leaves of Rhazya stricta. AU - Iqbal,Shahid, AU - Bhanger,M I, AU - Akhtar,Mubeena, AU - Anwar,Farooq, AU - Ahmed,Khawaja Raees, AU - Anwer,Tabraz, PY - 2006/7/11/pubmed PY - 2006/9/30/medline PY - 2006/7/11/entrez SP - 270 EP - 5 JF - Journal of medicinal food JO - J Med Food VL - 9 IS - 2 N2 - Because of increased safety concerns about synthetic antioxidants, exploitation of cheaper and safer sources of antioxidants based on natural origin is the focus of research nowadays. Rhazya stricta is a medicinally important plant native to South Asia. Extraction of antioxidants was carried out in different solvent systems, i.e., water, 80% methanol, 70% ethanol, and diethyl ether. The methanolic extract exhibited the highest total phenolic content among the extracts; therefore for further studies the methanolic extract was employed. Antioxidant activity measurement in the linoleic acid system, metal chelating activity, reducing power, scavenging effect on 1,1-diphenyl-2-picrylhydrazyl free radical, and superoxide anion radical scavenging activity were taken as the parameters for assessment of antioxidant potential of methanolic extracts. Results were compared with alpha-tocopherol and the synthetic antioxidant butylated hydroxyanisole. The antioxidant potential of methanolic extracts of R. stricta leaves was comparable with previously exploited potent antioxidants and is strongly concentration dependent. SN - 1096-620X UR - https://www.unboundmedicine.com/medline/citation/16822215/Antioxidant_properties_of_methanolic_extracts_from_leaves_of_Rhazya_stricta_ L2 - https://www.liebertpub.com/doi/10.1089/jmf.2006.9.270?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -