Tags

Type your tag names separated by a space and hit enter

Fulminant Lewy body disease.
Mov Disord. 2006 Oct; 21(10):1748-51.MD

Abstract

The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.

Authors+Show Affiliations

Department of Neurology, Geneva University Hospitals and Medical School, Geneva, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16830307

Citation

Momjian-Mayor, Isabelle, et al. "Fulminant Lewy Body Disease." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 21, no. 10, 2006, pp. 1748-51.
Momjian-Mayor I, Pizzolato GP, Burkhardt K, et al. Fulminant Lewy body disease. Mov Disord. 2006;21(10):1748-51.
Momjian-Mayor, I., Pizzolato, G. P., Burkhardt, K., Landis, T., Coeytaux, A., & Burkhard, P. R. (2006). Fulminant Lewy body disease. Movement Disorders : Official Journal of the Movement Disorder Society, 21(10), 1748-51.
Momjian-Mayor I, et al. Fulminant Lewy Body Disease. Mov Disord. 2006;21(10):1748-51. PubMed PMID: 16830307.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fulminant Lewy body disease. AU - Momjian-Mayor,Isabelle, AU - Pizzolato,Gian Paolo, AU - Burkhardt,Karim, AU - Landis,Theodor, AU - Coeytaux,Alessandra, AU - Burkhard,Pierre R, PY - 2006/7/11/pubmed PY - 2007/2/3/medline PY - 2006/7/11/entrez SP - 1748 EP - 51 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 21 IS - 10 N2 - The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/16830307/Fulminant_Lewy_body_disease_ L2 - https://doi.org/10.1002/mds.21034 DB - PRIME DP - Unbound Medicine ER -