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[Changes in serum and adipose tissue fatty acid composition after low calorie diet with respect to dietary fat content in obese].
Cas Lek Cesk. 2006; 145(6):464-9.CL

Abstract

BACKGROUND

Recently, a new attention has been paid to beneficial effects of high-fat diet on the body weight reduction and metabolic profile in obese subjects. In this study we compared the effects of two hypocaloric diets with different proportion of fat on fatty acid composition (FA) in blood and adipose tissue (AT).

METHODS AND RESULTS

Forty-four obese subjects were submitted to 10 weeks' low-calorie diet. Subjects were randomized into low-fat diet (LFD) (20-25% of energy content) and high-fat diet groups (HFD) (40-45%). Before and at the end of the intervention, samples of blood and subcutaneous AT were taken for the analysis of fatty acid composition. The diet-induced body weight and fat mass reduction were not different between the two diets. Plasma triacylglycerols (TAG) were reduced during HFD only. Both diets reduced proportion of n-3 polyunsaturated fatty acids in AT and of saturated fatty acid in blood TAG, with no difference between the diets. HFD induced a higher increase of monounsaturated fatty acids in blood TAG. No other diet-induced changes were found in proportion of major classes of fatty acids. In respect to individual fatty acids, the diets induced a number of changes in AT and blood, the changes, however, not being different between the diets.

CONCLUSION

Hypocaloric diets induce a number of changes in fatty acid composition in blood and adipose tissue, with little differences in respect to the proportion of fat in the diet. The results suggest the diet-induced changes in fatty acid composition are controlled by the calorie deficit of the diet and the proportion of dietary fat plays a minor role.

Authors+Show Affiliations

IV. interní klinika I. LF UK a VFN, Praha. marvec@volny.czNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial

Language

cze

PubMed ID

16835999

Citation

Vecka, M, et al. "[Changes in Serum and Adipose Tissue Fatty Acid Composition After Low Calorie Diet With Respect to Dietary Fat Content in Obese]." Casopis Lekaru Ceskych, vol. 145, no. 6, 2006, pp. 464-9.
Vecka M, Richterová B, Zák A, et al. [Changes in serum and adipose tissue fatty acid composition after low calorie diet with respect to dietary fat content in obese]. Cas Lek Cesk. 2006;145(6):464-9.
Vecka, M., Richterová, B., Zák, A., Tvrzická, E., Srámková, P., Stanková, B., Klimcáková, E., & Stich, V. (2006). [Changes in serum and adipose tissue fatty acid composition after low calorie diet with respect to dietary fat content in obese]. Casopis Lekaru Ceskych, 145(6), 464-9.
Vecka M, et al. [Changes in Serum and Adipose Tissue Fatty Acid Composition After Low Calorie Diet With Respect to Dietary Fat Content in Obese]. Cas Lek Cesk. 2006;145(6):464-9. PubMed PMID: 16835999.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Changes in serum and adipose tissue fatty acid composition after low calorie diet with respect to dietary fat content in obese]. AU - Vecka,M, AU - Richterová,B, AU - Zák,A, AU - Tvrzická,E, AU - Srámková,P, AU - Stanková,B, AU - Klimcáková,E, AU - Stich,V, PY - 2006/7/14/pubmed PY - 2006/9/13/medline PY - 2006/7/14/entrez SP - 464 EP - 9 JF - Casopis lekaru ceskych JO - Cas Lek Cesk VL - 145 IS - 6 N2 - BACKGROUND: Recently, a new attention has been paid to beneficial effects of high-fat diet on the body weight reduction and metabolic profile in obese subjects. In this study we compared the effects of two hypocaloric diets with different proportion of fat on fatty acid composition (FA) in blood and adipose tissue (AT). METHODS AND RESULTS: Forty-four obese subjects were submitted to 10 weeks' low-calorie diet. Subjects were randomized into low-fat diet (LFD) (20-25% of energy content) and high-fat diet groups (HFD) (40-45%). Before and at the end of the intervention, samples of blood and subcutaneous AT were taken for the analysis of fatty acid composition. The diet-induced body weight and fat mass reduction were not different between the two diets. Plasma triacylglycerols (TAG) were reduced during HFD only. Both diets reduced proportion of n-3 polyunsaturated fatty acids in AT and of saturated fatty acid in blood TAG, with no difference between the diets. HFD induced a higher increase of monounsaturated fatty acids in blood TAG. No other diet-induced changes were found in proportion of major classes of fatty acids. In respect to individual fatty acids, the diets induced a number of changes in AT and blood, the changes, however, not being different between the diets. CONCLUSION: Hypocaloric diets induce a number of changes in fatty acid composition in blood and adipose tissue, with little differences in respect to the proportion of fat in the diet. The results suggest the diet-induced changes in fatty acid composition are controlled by the calorie deficit of the diet and the proportion of dietary fat plays a minor role. SN - 0008-7335 UR - https://www.unboundmedicine.com/medline/citation/16835999/[Changes_in_serum_and_adipose_tissue_fatty_acid_composition_after_low_calorie_diet_with_respect_to_dietary_fat_content_in_obese]_ L2 - https://medlineplus.gov/obesity.html DB - PRIME DP - Unbound Medicine ER -