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Treatment of atopic dermatitis with the xenon chloride excimer laser.
J Eur Acad Dermatol Venereol. 2006 Jul; 20(6):657-60.JE

Abstract

BACKGROUND

Narrow-band ultraviolet B phototherapy is an effictive and safe treatment for atopic dermatitis. We have previously found that the 308 nm xenon chloride excimer laser was more effective than the narrow-band ultraviolet B light for the treatment of psoriasis, suggesting that ultraviolet B laser might offer advantages over narrow-band ultraviolet B.

OBJECTIVE

The purpose of this study was to evaluate the therapeutic efficacy of the 308 nm excimer laser in atopic dermatitis.

PATIENTS AND METHODS

Fifteen patients with atopic dermatitis (less than 20% body area involvement) were treated with a xenon chloride excimer laser (XTRAC laser, Photomedex Inc.) twice weekly. The severity of the atopic dermatitis was assessed via (i) a clinical score characterizing the intensity of erythema, infiltration, lichenification and excoriation; (ii) the quality of life, determined by means of a questionnaire; and (iii) a visual linear analogue scale, with which the patients scored the severity of their pruritus.

RESULTS

After 1 month of laser therapy, the clinical scores were significantly lower than the initial values. Similar decreases were observed for the quality of life and pruritus scores. No serious or unpleasant side-effects were observed.

CONCLUSION

These results suggest that the xenon chloride excimer laser is an effective and well-tolerated treatment for localized atopic dermatitis.

Authors+Show Affiliations

Department of Dermatology and Allergology, University of Szeged, H-6701, Szeged, PO Box 427, Hungary. baltas@derma.szote.u-szeged.huNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16836491

Citation

Baltás, E, et al. "Treatment of Atopic Dermatitis With the Xenon Chloride Excimer Laser." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 20, no. 6, 2006, pp. 657-60.
Baltás E, Csoma Z, Bodai L, et al. Treatment of atopic dermatitis with the xenon chloride excimer laser. J Eur Acad Dermatol Venereol. 2006;20(6):657-60.
Baltás, E., Csoma, Z., Bodai, L., Ignácz, F., Dobozy, A., & Kemény, L. (2006). Treatment of atopic dermatitis with the xenon chloride excimer laser. Journal of the European Academy of Dermatology and Venereology : JEADV, 20(6), 657-60.
Baltás E, et al. Treatment of Atopic Dermatitis With the Xenon Chloride Excimer Laser. J Eur Acad Dermatol Venereol. 2006;20(6):657-60. PubMed PMID: 16836491.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of atopic dermatitis with the xenon chloride excimer laser. AU - Baltás,E, AU - Csoma,Z, AU - Bodai,L, AU - Ignácz,F, AU - Dobozy,A, AU - Kemény,L, PY - 2006/7/14/pubmed PY - 2006/12/9/medline PY - 2006/7/14/entrez SP - 657 EP - 60 JF - Journal of the European Academy of Dermatology and Venereology : JEADV JO - J Eur Acad Dermatol Venereol VL - 20 IS - 6 N2 - BACKGROUND: Narrow-band ultraviolet B phototherapy is an effictive and safe treatment for atopic dermatitis. We have previously found that the 308 nm xenon chloride excimer laser was more effective than the narrow-band ultraviolet B light for the treatment of psoriasis, suggesting that ultraviolet B laser might offer advantages over narrow-band ultraviolet B. OBJECTIVE: The purpose of this study was to evaluate the therapeutic efficacy of the 308 nm excimer laser in atopic dermatitis. PATIENTS AND METHODS: Fifteen patients with atopic dermatitis (less than 20% body area involvement) were treated with a xenon chloride excimer laser (XTRAC laser, Photomedex Inc.) twice weekly. The severity of the atopic dermatitis was assessed via (i) a clinical score characterizing the intensity of erythema, infiltration, lichenification and excoriation; (ii) the quality of life, determined by means of a questionnaire; and (iii) a visual linear analogue scale, with which the patients scored the severity of their pruritus. RESULTS: After 1 month of laser therapy, the clinical scores were significantly lower than the initial values. Similar decreases were observed for the quality of life and pruritus scores. No serious or unpleasant side-effects were observed. CONCLUSION: These results suggest that the xenon chloride excimer laser is an effective and well-tolerated treatment for localized atopic dermatitis. SN - 0926-9959 UR - https://www.unboundmedicine.com/medline/citation/16836491/Treatment_of_atopic_dermatitis_with_the_xenon_chloride_excimer_laser_ L2 - https://doi.org/10.1111/j.1468-3083.2006.01495.x DB - PRIME DP - Unbound Medicine ER -