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Orientia tsutsugamushi in eschars from scrub typhus patients.
Emerg Infect Dis. 2006 Jul; 12(7):1109-12.EI

Abstract

To verify the value of eschars for the diagnosis of scrub typhus and to characterize genotypes of Orientia tsutsugamushi in patients, we examined eschars and blood specimens of 7 patients from Shandong Province, People's Republic of China, for O. tsutsugamushi by polymerase chain reaction targeting the Sta56 gene. All 7 eschars and acute-phase blood samples were positive, while no specific DNA amplicons were obtained from the 7 convalescent-phase blood samples collected after antimicrobial drug therapy. The findings indicate that patients' eschars can be used for detection and genetic characterization of O. tsutsugamushi during the convalescent phase.

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Authors+Show Affiliations

Liu YX
Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Cao WC
No affiliation info available
Gao Y
No affiliation info available
Zhang JL
No affiliation info available
Yang ZQ
No affiliation info available
Zhao ZT
No affiliation info available
Foley JE
No affiliation info available

MeSH

AdultAntibodies, BacterialChinaFemaleHumansMaleMiddle AgedOrientia tsutsugamushiScrub Typhus

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16836828

Citation

Liu, Yun-Xi, et al. "Orientia Tsutsugamushi in Eschars From Scrub Typhus Patients." Emerging Infectious Diseases, vol. 12, no. 7, 2006, pp. 1109-12.
Liu YX, Cao WC, Gao Y, et al. Orientia tsutsugamushi in eschars from scrub typhus patients. Emerg Infect Dis. 2006;12(7):1109-12.
Liu, Y. X., Cao, W. C., Gao, Y., Zhang, J. L., Yang, Z. Q., Zhao, Z. T., & Foley, J. E. (2006). Orientia tsutsugamushi in eschars from scrub typhus patients. Emerging Infectious Diseases, 12(7), 1109-12.
Liu YX, et al. Orientia Tsutsugamushi in Eschars From Scrub Typhus Patients. Emerg Infect Dis. 2006;12(7):1109-12. PubMed PMID: 16836828.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Orientia tsutsugamushi in eschars from scrub typhus patients. AU - Liu,Yun-Xi, AU - Cao,Wu-Chun, AU - Gao,Yuan, AU - Zhang,Jing-Lan, AU - Yang,Zhan-Qing, AU - Zhao,Zhong-Tang, AU - Foley,Janet E, PY - 2006/7/14/pubmed PY - 2006/9/7/medline PY - 2006/7/14/entrez SP - 1109 EP - 12 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 12 IS - 7 N2 - To verify the value of eschars for the diagnosis of scrub typhus and to characterize genotypes of Orientia tsutsugamushi in patients, we examined eschars and blood specimens of 7 patients from Shandong Province, People's Republic of China, for O. tsutsugamushi by polymerase chain reaction targeting the Sta56 gene. All 7 eschars and acute-phase blood samples were positive, while no specific DNA amplicons were obtained from the 7 convalescent-phase blood samples collected after antimicrobial drug therapy. The findings indicate that patients' eschars can be used for detection and genetic characterization of O. tsutsugamushi during the convalescent phase. SN - 1080-6040 UR - https://www.unboundmedicine.com/medline/citation/16836828/Orientia_tsutsugamushi_in_eschars_from_scrub_typhus_patients_ L2 - https://www.cdc.gov/ncidod/eid/vol12no07/05-0827.htm DB - PRIME DP - Unbound Medicine ER -