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Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A beta-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis.
J Med Microbiol. 2006 Aug; 55(Pt 8):989-992.JM

Abstract

The inflamed tonsils harbour numerous types of bacteria, alone or in combination with group A beta-haemolytic streptococci (GABHS). The cohabitation of the tonsils by GABHS and certain other bacterial species may contribute to the inflammatory process and the failure of penicillin therapy. This study evaluated the recovery of Moraxella catarrhalis, Haemophilus influenzae, Staphylococcus aureus and Streptococcus pneumoniae in association with GABHS in healthy children and those with acute pharyngo-tonsillitis (APT). Pharyngo-tonsillar cultures were obtained from 548 children with APT and 866 healthy children. GABHS was recovered from 112 (20.4%) children with APT. Of the 114 H. influenzae isolates, 32 were recovered in association with GABHS (29% of all patients who had GABHS) and 82 were isolated without GABHS (19%) (P=0.0267). Of the 69 M. catarrhalis isolates, 25 were recovered in association with GABHS (22% of all patients who had GABHS) and 44 were isolated without GABHS (10%) (P=0.0012). In contrast, there was no association between the isolation of GABHS and the recovery of Staph. aureus or Strep. pneumoniae. GABHS was recovered from 104 (12%) healthy children. Of the 69 M. catarrhalis isolates, 24 were recovered in association with GABHS (23% of all patients who had GABHS) and 80 were isolated without GABHS (10%) (P=0.006). There was no association between the isolation of GABHS and the recovery of H. influenzae, Staph. aureus or Strep. pneumoniae. This study demonstrates an association between the recovery of GABHS and H. influenzae and M. catarrhalis from pharyngo-tonsillar cultures of patients with APT and M. catarrhalis from pharyngo-tonsillar cultures of healthy children.

Authors+Show Affiliations

Department of Pediatrics, Georgetown University, School of Medicine, Washington, DC, USA.Department of Pediatrics, Georgetown University, School of Medicine, Washington, DC, USA.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16849717

Citation

Brook, Itzhak, and Alan E. Gober. "Increased Recovery of Moraxella Catarrhalis and Haemophilus Influenzae in Association With Group a Beta-haemolytic Streptococci in Healthy Children and Those With Pharyngo-tonsillitis." Journal of Medical Microbiology, vol. 55, no. Pt 8, 2006, pp. 989-992.
Brook I, Gober AE. Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A beta-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis. J Med Microbiol. 2006;55(Pt 8):989-992.
Brook, I., & Gober, A. E. (2006). Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A beta-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis. Journal of Medical Microbiology, 55(Pt 8), 989-992. https://doi.org/10.1099/jmm.0.46325-0
Brook I, Gober AE. Increased Recovery of Moraxella Catarrhalis and Haemophilus Influenzae in Association With Group a Beta-haemolytic Streptococci in Healthy Children and Those With Pharyngo-tonsillitis. J Med Microbiol. 2006;55(Pt 8):989-992. PubMed PMID: 16849717.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A beta-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis. AU - Brook,Itzhak, AU - Gober,Alan E, PY - 2006/7/20/pubmed PY - 2006/9/15/medline PY - 2006/7/20/entrez SP - 989 EP - 992 JF - Journal of medical microbiology JO - J Med Microbiol VL - 55 IS - Pt 8 N2 - The inflamed tonsils harbour numerous types of bacteria, alone or in combination with group A beta-haemolytic streptococci (GABHS). The cohabitation of the tonsils by GABHS and certain other bacterial species may contribute to the inflammatory process and the failure of penicillin therapy. This study evaluated the recovery of Moraxella catarrhalis, Haemophilus influenzae, Staphylococcus aureus and Streptococcus pneumoniae in association with GABHS in healthy children and those with acute pharyngo-tonsillitis (APT). Pharyngo-tonsillar cultures were obtained from 548 children with APT and 866 healthy children. GABHS was recovered from 112 (20.4%) children with APT. Of the 114 H. influenzae isolates, 32 were recovered in association with GABHS (29% of all patients who had GABHS) and 82 were isolated without GABHS (19%) (P=0.0267). Of the 69 M. catarrhalis isolates, 25 were recovered in association with GABHS (22% of all patients who had GABHS) and 44 were isolated without GABHS (10%) (P=0.0012). In contrast, there was no association between the isolation of GABHS and the recovery of Staph. aureus or Strep. pneumoniae. GABHS was recovered from 104 (12%) healthy children. Of the 69 M. catarrhalis isolates, 24 were recovered in association with GABHS (23% of all patients who had GABHS) and 80 were isolated without GABHS (10%) (P=0.006). There was no association between the isolation of GABHS and the recovery of H. influenzae, Staph. aureus or Strep. pneumoniae. This study demonstrates an association between the recovery of GABHS and H. influenzae and M. catarrhalis from pharyngo-tonsillar cultures of patients with APT and M. catarrhalis from pharyngo-tonsillar cultures of healthy children. SN - 0022-2615 UR - https://www.unboundmedicine.com/medline/citation/16849717/Increased_recovery_of_Moraxella_catarrhalis_and_Haemophilus_influenzae_in_association_with_group_A_beta_haemolytic_streptococci_in_healthy_children_and_those_with_pharyngo_tonsillitis_ L2 - http://jmm.microbiologyresearch.org/pubmed/content/journal/jmm/10.1099/jmm.0.46325-0 DB - PRIME DP - Unbound Medicine ER -