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Secondary cutaneous effects of hydroxyurea: possible pathogenetic mechanisms.
J Dermatolog Treat. 2006; 17(3):176-8.JD

Abstract

We report the case of a 73-year-old man who had been on hydroxyurea for essential thrombocythemia since 1988. After 12 years of treatment he developed a symmetrical dermatomyositis-like eruption together with a leg ulceration and five squamous cell carcinomas of the face. The possible pathogenetic mechanisms of these known side effects are discussed.

Authors+Show Affiliations

Di.S.E.M. Department of Endocrinological and Metabolic Science, Section of Dermatology, University of Genoa, Genoa, Italy.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16854761

Citation

Zaccaria, Elisa, et al. "Secondary Cutaneous Effects of Hydroxyurea: Possible Pathogenetic Mechanisms." The Journal of Dermatological Treatment, vol. 17, no. 3, 2006, pp. 176-8.
Zaccaria E, Cozzani E, Parodi A. Secondary cutaneous effects of hydroxyurea: possible pathogenetic mechanisms. J Dermatolog Treat. 2006;17(3):176-8.
Zaccaria, E., Cozzani, E., & Parodi, A. (2006). Secondary cutaneous effects of hydroxyurea: possible pathogenetic mechanisms. The Journal of Dermatological Treatment, 17(3), 176-8.
Zaccaria E, Cozzani E, Parodi A. Secondary Cutaneous Effects of Hydroxyurea: Possible Pathogenetic Mechanisms. J Dermatolog Treat. 2006;17(3):176-8. PubMed PMID: 16854761.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Secondary cutaneous effects of hydroxyurea: possible pathogenetic mechanisms. AU - Zaccaria,Elisa, AU - Cozzani,Emanuele, AU - Parodi,Aurora, PY - 2006/7/21/pubmed PY - 2006/10/13/medline PY - 2006/7/21/entrez SP - 176 EP - 8 JF - The Journal of dermatological treatment JO - J Dermatolog Treat VL - 17 IS - 3 N2 - We report the case of a 73-year-old man who had been on hydroxyurea for essential thrombocythemia since 1988. After 12 years of treatment he developed a symmetrical dermatomyositis-like eruption together with a leg ulceration and five squamous cell carcinomas of the face. The possible pathogenetic mechanisms of these known side effects are discussed. SN - 0954-6634 UR - https://www.unboundmedicine.com/medline/citation/16854761/Secondary_cutaneous_effects_of_hydroxyurea:_possible_pathogenetic_mechanisms_ L2 - https://www.tandfonline.com/doi/full/10.1080/09546630600780494 DB - PRIME DP - Unbound Medicine ER -