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Bone mineral density among patients undergoing continuous ambulatory peritoneal dialysis (CAPD).
J Med Assoc Thai. 2005 Oct; 88 Suppl 5:S40-5.JM

Abstract

Apart from the conventional risks, low bone mineral density (BMD) is one of the risk factors for bone fracture. Interestingly, the incidence of bone fracture is highest among patients with chronic renal failure, but there is little data comparing the BMD of patients undergoing continuous ambulatory peritoneal dialysis (CAPD) with normal persons. The authors, therefore, compared the BMD between sex-, age- and bodyweight-matched CAPD patients and normal persons. The femoral neck, lumbar spine and total BMD were measured by dual energy X-ray absorptiometry in 62 CAPD patients and normal persons. In unadjusted analysis, femoral neck and total BMD in CAPD patients was significantly lower than normal controls in both men and women, while there was no significant difference at lumbar spine BMD between the two groups. The results were unchanged after adjusting for age, body weight and height (0.13 and 0.29 g/cm2, p < 0.001, for femoral and total BMD, respectively and 0.001 g/cm2, p = 0.96 for lumbar spine BMD). In conclusion, low BMD is already a major risk factor for hip fracture, and this risk is exacerbated by CAPD. BMD measurement should be incorporated into the routine care of CAPD patients in order to identify incipient osteoporosis, so that it may be treated to prevent fractures.

Authors+Show Affiliations

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. pchatl@kku.ac.thNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16869106

Citation

Pongchaiyakul, Chatlert, et al. "Bone Mineral Density Among Patients Undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD)." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 88 Suppl 5, 2005, pp. S40-5.
Pongchaiyakul C, Pongskul C, Ruengjui S, et al. Bone mineral density among patients undergoing continuous ambulatory peritoneal dialysis (CAPD). J Med Assoc Thai. 2005;88 Suppl 5:S40-5.
Pongchaiyakul, C., Pongskul, C., Ruengjui, S., & Sirivongs, D. (2005). Bone mineral density among patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 88 Suppl 5, S40-5.
Pongchaiyakul C, et al. Bone Mineral Density Among Patients Undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD). J Med Assoc Thai. 2005;88 Suppl 5:S40-5. PubMed PMID: 16869106.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bone mineral density among patients undergoing continuous ambulatory peritoneal dialysis (CAPD). AU - Pongchaiyakul,Chatlert, AU - Pongskul,Cholatip, AU - Ruengjui,Sirirat, AU - Sirivongs,Dhavee, PY - 2006/7/28/pubmed PY - 2006/9/13/medline PY - 2006/7/28/entrez SP - S40 EP - 5 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 88 Suppl 5 N2 - Apart from the conventional risks, low bone mineral density (BMD) is one of the risk factors for bone fracture. Interestingly, the incidence of bone fracture is highest among patients with chronic renal failure, but there is little data comparing the BMD of patients undergoing continuous ambulatory peritoneal dialysis (CAPD) with normal persons. The authors, therefore, compared the BMD between sex-, age- and bodyweight-matched CAPD patients and normal persons. The femoral neck, lumbar spine and total BMD were measured by dual energy X-ray absorptiometry in 62 CAPD patients and normal persons. In unadjusted analysis, femoral neck and total BMD in CAPD patients was significantly lower than normal controls in both men and women, while there was no significant difference at lumbar spine BMD between the two groups. The results were unchanged after adjusting for age, body weight and height (0.13 and 0.29 g/cm2, p < 0.001, for femoral and total BMD, respectively and 0.001 g/cm2, p = 0.96 for lumbar spine BMD). In conclusion, low BMD is already a major risk factor for hip fracture, and this risk is exacerbated by CAPD. BMD measurement should be incorporated into the routine care of CAPD patients in order to identify incipient osteoporosis, so that it may be treated to prevent fractures. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/16869106/Bone_mineral_density_among_patients_undergoing_continuous_ambulatory_peritoneal_dialysis__CAPD__ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -