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Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress.
Patient Educ Couns. 2007 Jan; 65(1):58-68.PE

Abstract

OBJECTIVE

To study differences between individuals opting for genetic cancer susceptibility testing of a known familial BRCA1/2 and HNPCC related germline mutation.

METHODS

Coping, illness perceptions, experiences with cancer in relatives and family system characteristics were assessed in 271 applicants for genetic testing before test result disclosure. Hereditary cancer distress, worry and cancer risk perception were assessed before, 1 week after, and 6 months after disclosure.

RESULTS

Individuals from BRCA1/2 and HNPCC mutation families did not differ with regard to the number of experiences with cancer in relatives, grief symptoms, the course of cancer distress, worry and risk perception through time and most illness perceptions, coping responses and family characteristics. Individuals from BRCA1/2 families perceived hereditary cancer as more serious. They reported more frequently a passive coping style, cancer worry and a less open communication with their partner and children.

CONCLUSION

Besides subtle differences, psychological mechanisms may be mainly identical in individuals opting for BRCA1/2 and HNPCC susceptibility testing.

PRACTICE IMPLICATIONS

Based on our findings, using a similar counseling approach for individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing is justified. In this approach, attention should be directed more to individual aspects than to the type of disorder.

Authors+Show Affiliations

Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, The Netherlands.i.vanoostrom@erasmusmc.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16872788

Citation

van Oostrom, Iris, et al. "Comparison of Individuals Opting for BRCA1/2 or HNPCC Genetic Susceptibility Testing With Regard to Coping, Illness Perceptions, Illness Experiences, Family System Characteristics and Hereditary Cancer Distress." Patient Education and Counseling, vol. 65, no. 1, 2007, pp. 58-68.
van Oostrom I, Meijers-Heijboer H, Duivenvoorden HJ, et al. Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress. Patient Educ Couns. 2007;65(1):58-68.
van Oostrom, I., Meijers-Heijboer, H., Duivenvoorden, H. J., Bröcker-Vriends, A. H., van Asperen, C. J., Sijmons, R. H., Seynaeve, C., Van Gool, A. R., Klijn, J. G., & Tibben, A. (2007). Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress. Patient Education and Counseling, 65(1), 58-68.
van Oostrom I, et al. Comparison of Individuals Opting for BRCA1/2 or HNPCC Genetic Susceptibility Testing With Regard to Coping, Illness Perceptions, Illness Experiences, Family System Characteristics and Hereditary Cancer Distress. Patient Educ Couns. 2007;65(1):58-68. PubMed PMID: 16872788.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress. AU - van Oostrom,Iris, AU - Meijers-Heijboer,Hanne, AU - Duivenvoorden,Hugo J, AU - Bröcker-Vriends,Annette H J T, AU - van Asperen,Christi J, AU - Sijmons,Rolf H, AU - Seynaeve,Caroline, AU - Van Gool,Arthur R, AU - Klijn,Jan G M, AU - Tibben,Aad, Y1 - 2006/07/26/ PY - 2006/02/02/received PY - 2006/04/26/revised PY - 2006/05/01/accepted PY - 2006/7/29/pubmed PY - 2007/2/24/medline PY - 2006/7/29/entrez SP - 58 EP - 68 JF - Patient education and counseling JO - Patient Educ Couns VL - 65 IS - 1 N2 - OBJECTIVE: To study differences between individuals opting for genetic cancer susceptibility testing of a known familial BRCA1/2 and HNPCC related germline mutation. METHODS: Coping, illness perceptions, experiences with cancer in relatives and family system characteristics were assessed in 271 applicants for genetic testing before test result disclosure. Hereditary cancer distress, worry and cancer risk perception were assessed before, 1 week after, and 6 months after disclosure. RESULTS: Individuals from BRCA1/2 and HNPCC mutation families did not differ with regard to the number of experiences with cancer in relatives, grief symptoms, the course of cancer distress, worry and risk perception through time and most illness perceptions, coping responses and family characteristics. Individuals from BRCA1/2 families perceived hereditary cancer as more serious. They reported more frequently a passive coping style, cancer worry and a less open communication with their partner and children. CONCLUSION: Besides subtle differences, psychological mechanisms may be mainly identical in individuals opting for BRCA1/2 and HNPCC susceptibility testing. PRACTICE IMPLICATIONS: Based on our findings, using a similar counseling approach for individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing is justified. In this approach, attention should be directed more to individual aspects than to the type of disorder. SN - 0738-3991 UR - https://www.unboundmedicine.com/medline/citation/16872788/Comparison_of_individuals_opting_for_BRCA1/2_or_HNPCC_genetic_susceptibility_testing_with_regard_to_coping_illness_perceptions_illness_experiences_family_system_characteristics_and_hereditary_cancer_distress_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0738-3991(06)00160-1 DB - PRIME DP - Unbound Medicine ER -