Tags

Type your tag names separated by a space and hit enter

Multicenter evaluation of the breast lesion excision system, a percutaneous, vacuum-assisted, intact-specimen breast biopsy device.
Cancer. 2006 Sep 01; 107(5):945-9.C

Abstract

BACKGROUND

Percutaneous, vacuum-assisted, large-gauge core needle biopsy (VACNB) provides an alternative to open surgical biopsy as an initial diagnostic tool for breast lesions, yet rates of underestimating malignant diagnoses remain sufficiently high to warrant surgical biopsy in some cases. The current study was performed to determine if the Breast Lesion Excision System (BLES) provides a feasible alternative to VACNB.

METHODS

A retrospective review was conducted of 742 consecutive mammographic lesions with microcalcifications classified as Breast Imaging Reporting and Data System (BIRADS) IV or V that had stereotactic percutaneous biopsy using BLES. Initial diagnoses obtained from the histopathologic examination of tissues retrieved at biopsy were compared with the histopathologic examination of tissues received from surgical excision or lumpectomy. Underestimation rates for atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS) were recorded if open surgical biopsy revealed DCIS or invasive cancer, and invasive cancer, respectively.

RESULTS

Of the 742 breast lesions, 34 displayed ADH upon biopsy with the BLES device. Two patients did not receive open surgical biopsy. Of the 32 patients who had open surgical excision, 3 (9.4%) had DCIS or invasive cancer. There were 119 diagnoses of DCIS upon biopsy with the BLES device. Four patients did not receive open surgical biopsy. Of the 115 patients who had open surgical excision, 6 (5.2%) had invasive cancer.

CONCLUSIONS

Breast biopsy can be performed accurately using the BLES device. Compared with VACNB, it does not alter the need for surgical excision in women diagnosed with ADH or DCIS at core biopsy.

Links

Aggregator Full Text

Authors+Show Affiliations

Sie A
Long Beach Memorial Breast Center, Long Beach, California 90086, USA. asie@memorialcare.org
Bryan DC
No affiliation info available
Gaines V
No affiliation info available
Killebrew LK
No affiliation info available
Kim CH
No affiliation info available
Morrison CC
No affiliation info available
Poller WR
No affiliation info available
Romilly AP
No affiliation info available
Schilling K
No affiliation info available
Sung JH
No affiliation info available

MeSH

Biopsy, NeedleBreastBreast DiseasesBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingFalse Negative ReactionsFemaleHumansHyperplasiaRetrospective StudiesVacuum

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article
Multicenter Study

Language

eng

PubMed ID

16874817

Clinical Trial Links

Minimal Invasive Breast Cancer Excision Using the Breast Lesion Excision System Under Ultrasound Guidance

Citation

Sie, Angela, et al. "Multicenter Evaluation of the Breast Lesion Excision System, a Percutaneous, Vacuum-assisted, Intact-specimen Breast Biopsy Device." Cancer, vol. 107, no. 5, 2006, pp. 945-9.
Sie A, Bryan DC, Gaines V, et al. Multicenter evaluation of the breast lesion excision system, a percutaneous, vacuum-assisted, intact-specimen breast biopsy device. Cancer. 2006;107(5):945-9.
Sie, A., Bryan, D. C., Gaines, V., Killebrew, L. K., Kim, C. H., Morrison, C. C., Poller, W. R., Romilly, A. P., Schilling, K., & Sung, J. H. (2006). Multicenter evaluation of the breast lesion excision system, a percutaneous, vacuum-assisted, intact-specimen breast biopsy device. Cancer, 107(5), 945-9.
Sie A, et al. Multicenter Evaluation of the Breast Lesion Excision System, a Percutaneous, Vacuum-assisted, Intact-specimen Breast Biopsy Device. Cancer. 2006 Sep 1;107(5):945-9. PubMed PMID: 16874817.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multicenter evaluation of the breast lesion excision system, a percutaneous, vacuum-assisted, intact-specimen breast biopsy device. AU - Sie,Angela, AU - Bryan,David C, AU - Gaines,Victor, AU - Killebrew,Larry K, AU - Kim,Christine H, AU - Morrison,Carrie C, AU - Poller,William R, AU - Romilly,Ada P, AU - Schilling,Kathy, AU - Sung,Janet H, PY - 2006/7/29/pubmed PY - 2006/10/3/medline PY - 2006/7/29/entrez SP - 945 EP - 9 JF - Cancer JO - Cancer VL - 107 IS - 5 N2 - BACKGROUND: Percutaneous, vacuum-assisted, large-gauge core needle biopsy (VACNB) provides an alternative to open surgical biopsy as an initial diagnostic tool for breast lesions, yet rates of underestimating malignant diagnoses remain sufficiently high to warrant surgical biopsy in some cases. The current study was performed to determine if the Breast Lesion Excision System (BLES) provides a feasible alternative to VACNB. METHODS: A retrospective review was conducted of 742 consecutive mammographic lesions with microcalcifications classified as Breast Imaging Reporting and Data System (BIRADS) IV or V that had stereotactic percutaneous biopsy using BLES. Initial diagnoses obtained from the histopathologic examination of tissues retrieved at biopsy were compared with the histopathologic examination of tissues received from surgical excision or lumpectomy. Underestimation rates for atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS) were recorded if open surgical biopsy revealed DCIS or invasive cancer, and invasive cancer, respectively. RESULTS: Of the 742 breast lesions, 34 displayed ADH upon biopsy with the BLES device. Two patients did not receive open surgical biopsy. Of the 32 patients who had open surgical excision, 3 (9.4%) had DCIS or invasive cancer. There were 119 diagnoses of DCIS upon biopsy with the BLES device. Four patients did not receive open surgical biopsy. Of the 115 patients who had open surgical excision, 6 (5.2%) had invasive cancer. CONCLUSIONS: Breast biopsy can be performed accurately using the BLES device. Compared with VACNB, it does not alter the need for surgical excision in women diagnosed with ADH or DCIS at core biopsy. SN - 0008-543X UR - https://www.unboundmedicine.com/medline/citation/16874817/Multicenter_evaluation_of_the_breast_lesion_excision_system_a_percutaneous_vacuum_assisted_intact_specimen_breast_biopsy_device_ L2 - https://doi.org/10.1002/cncr.22090 DB - PRIME DP - Unbound Medicine ER -