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Quality of life in patients with symptomatic multivessel coronary artery disease: a comparative post hoc analyses of medical, angioplasty or surgical strategies-MASS II trial.
Int J Cardiol. 2007 Apr 04; 116(3):364-70.IJ

Abstract

OBJECTIVE

We evaluated the impact of Coronary Artery Bypass Graft Surgery (CABG), Percutaneous Coronary Intervention (PCI) or Medical Therapy (MT) on self-perceived quality of life among patients with stable Coronary Artery Disease (CAD).

BACKGROUND

The Medicine, Angioplasty and Surgery Study (MASS-II) implemented initial policies of CABG, PCI or continued medical treatment in patients who allow assessment of mid-term health consequences.

METHODS

A total of 542 patients were randomly assigned to CABG (175), to PCI (180) and to MT (187). The short form 36 (SF-36) self-administered quality of life (QoL) questionnaires were applied at baseline, 6 months and 12 months later.

RESULTS

All the three therapeutic strategies presented significant improvement in all dimensions of the SF-36 during the follow-up (p<0.0001). However, the CABG group was the one that had significantly greater improvement in physical and social functioning, vitality and general health when compared to MT and PCI. Also, men had the best QoL at the beginning of the treatment when compared to women, with a progressive improvement after 6 and 12 months.

CONCLUSIONS

The quality of life was better in both CABG and PCI groups compared to MT after 1 year of follow-up. However, the patients submitted to CABG were the ones that presented the greater and progressive improvement of QoL. Also, men presented better QoL at the beginning and after treatment when compared to women.

Authors+Show Affiliations

Heart Institute (InCor), University of Sao Paulo School of Medicine, Sao Paulo, SP, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16876891

Citation

Favarato, Maria Elenita, et al. "Quality of Life in Patients With Symptomatic Multivessel Coronary Artery Disease: a Comparative Post Hoc Analyses of Medical, Angioplasty or Surgical strategies-MASS II Trial." International Journal of Cardiology, vol. 116, no. 3, 2007, pp. 364-70.
Favarato ME, Hueb W, Boden WE, et al. Quality of life in patients with symptomatic multivessel coronary artery disease: a comparative post hoc analyses of medical, angioplasty or surgical strategies-MASS II trial. Int J Cardiol. 2007;116(3):364-70.
Favarato, M. E., Hueb, W., Boden, W. E., Lopes, N., Nogueira, C. R., Takiuti, M., Góis, A. F., Borges, J. C., Favarato, D., Aldrighi, J. M., Oliveira, S. A., & Ramires, J. A. (2007). Quality of life in patients with symptomatic multivessel coronary artery disease: a comparative post hoc analyses of medical, angioplasty or surgical strategies-MASS II trial. International Journal of Cardiology, 116(3), 364-70.
Favarato ME, et al. Quality of Life in Patients With Symptomatic Multivessel Coronary Artery Disease: a Comparative Post Hoc Analyses of Medical, Angioplasty or Surgical strategies-MASS II Trial. Int J Cardiol. 2007 Apr 4;116(3):364-70. PubMed PMID: 16876891.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quality of life in patients with symptomatic multivessel coronary artery disease: a comparative post hoc analyses of medical, angioplasty or surgical strategies-MASS II trial. AU - Favarato,Maria Elenita, AU - Hueb,Whady, AU - Boden,William E, AU - Lopes,Neuza, AU - Nogueira,Célia Regina Simões da Rocha, AU - Takiuti,Myrthes, AU - Góis,Aécio F T, AU - Borges,Jorge C, AU - Favarato,Desiderio, AU - Aldrighi,Jose Mendes, AU - Oliveira,Sérgio Almeida, AU - Ramires,José A F, Y1 - 2006/07/28/ PY - 2005/06/17/received PY - 2006/04/13/revised PY - 2006/06/02/accepted PY - 2006/8/1/pubmed PY - 2007/3/3/medline PY - 2006/8/1/entrez SP - 364 EP - 70 JF - International journal of cardiology JO - Int J Cardiol VL - 116 IS - 3 N2 - OBJECTIVE: We evaluated the impact of Coronary Artery Bypass Graft Surgery (CABG), Percutaneous Coronary Intervention (PCI) or Medical Therapy (MT) on self-perceived quality of life among patients with stable Coronary Artery Disease (CAD). BACKGROUND: The Medicine, Angioplasty and Surgery Study (MASS-II) implemented initial policies of CABG, PCI or continued medical treatment in patients who allow assessment of mid-term health consequences. METHODS: A total of 542 patients were randomly assigned to CABG (175), to PCI (180) and to MT (187). The short form 36 (SF-36) self-administered quality of life (QoL) questionnaires were applied at baseline, 6 months and 12 months later. RESULTS: All the three therapeutic strategies presented significant improvement in all dimensions of the SF-36 during the follow-up (p<0.0001). However, the CABG group was the one that had significantly greater improvement in physical and social functioning, vitality and general health when compared to MT and PCI. Also, men had the best QoL at the beginning of the treatment when compared to women, with a progressive improvement after 6 and 12 months. CONCLUSIONS: The quality of life was better in both CABG and PCI groups compared to MT after 1 year of follow-up. However, the patients submitted to CABG were the ones that presented the greater and progressive improvement of QoL. Also, men presented better QoL at the beginning and after treatment when compared to women. SN - 1874-1754 UR - https://www.unboundmedicine.com/medline/citation/16876891/Quality_of_life_in_patients_with_symptomatic_multivessel_coronary_artery_disease:_a_comparative_post_hoc_analyses_of_medical_angioplasty_or_surgical_strategies_MASS_II_trial_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-5273(06)00478-5 DB - PRIME DP - Unbound Medicine ER -