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The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation.
Pacing Clin Electrophysiol. 2006 Jul; 29(7):727-32.PC

Abstract

BACKGROUND

Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF.

METHODS

Seventy-two patients (36 M, aged 77 +/- 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients.

RESULTS

OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P < 0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 +/- 13 vs 36 +/- 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 +/- 0.6 vs 2.0 +/- 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups.

CONCLUSION

Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA.

Authors+Show Affiliations

Internal Medicine and Cardiology, University of Firenze, Firenze, Italy. lpadeletti@interfree.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16884508

Citation

Padeletti, Luigi, et al. "The Risk Profile for Obstructive Sleep Apnea Does Not Affect the Recurrence of Atrial Fibrillation." Pacing and Clinical Electrophysiology : PACE, vol. 29, no. 7, 2006, pp. 727-32.
Padeletti L, Gensini GF, Pieragnoli P, et al. The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. Pacing Clin Electrophysiol. 2006;29(7):727-32.
Padeletti, L., Gensini, G. F., Pieragnoli, P., Ravazzi, P., Diotallevi, P., Baldi, N., Russo, V., Orazi, S., Occhetta, E., Padeletti, M., Corbucci, G., Jelic, S., & Barold, S. S. (2006). The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. Pacing and Clinical Electrophysiology : PACE, 29(7), 727-32.
Padeletti L, et al. The Risk Profile for Obstructive Sleep Apnea Does Not Affect the Recurrence of Atrial Fibrillation. Pacing Clin Electrophysiol. 2006;29(7):727-32. PubMed PMID: 16884508.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillation. AU - Padeletti,Luigi, AU - Gensini,Gian Franco, AU - Pieragnoli,Paolo, AU - Ravazzi,Pierantonio, AU - Diotallevi,Paolo, AU - Baldi,Nicola, AU - Russo,Vitantonio, AU - Orazi,Serafino, AU - Occhetta,Eraldo, AU - Padeletti,Margherita, AU - Corbucci,Giorgio, AU - Jelic,Sanja, AU - Barold,S Serge, PY - 2006/8/4/pubmed PY - 2006/12/9/medline PY - 2006/8/4/entrez SP - 727 EP - 32 JF - Pacing and clinical electrophysiology : PACE JO - Pacing Clin Electrophysiol VL - 29 IS - 7 N2 - BACKGROUND: Obstructive sleep apnea (OSA) has been linked to increased prevalence and recurrence of atrial fibrillation (AF). We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF. METHODS: Seventy-two patients (36 M, aged 77 +/- 6 years) completed the study. All patients received a dual-chamber pacemaker equipped with diagnostic and preventive functions for AF. OSA was diagnosed with the Berlin Questionnaire, which is validated to identify patients with OSA. Four-month continuous pacemaker recordings were collected for all patients. RESULTS: OSA was diagnosed in 28% of patients. Patients at high risk for OSA (HR group) and patients at low risk for OSA (LR group) were equivalent for gender, age, and body mass index. The rate of hypertension was higher in HR than in LR group (90% vs 44%, P < 0.01). The prevalence of paroxysmal AF during the study period was similar in HR and LR group (53% vs 44%, P = NS). Overall number of AF episodes per month was not significantly different between HR and LR group (7 +/- 13 vs 36 +/- 122, P = NS). Similarly, AF burden (AF%) was not significantly different between HR and LR group (0.3 +/- 0.6 vs 2.0 +/- 4.8, P = NS). Circadian distribution of AF episodes was similar in both groups. CONCLUSION: Long-term pacemaker recording of AF recurrence, AF burden, and its circadian distribution is similar in patients with paroxysmal AF at high risk for OSA and those at low risk for OSA. SN - 0147-8389 UR - https://www.unboundmedicine.com/medline/citation/16884508/The_risk_profile_for_obstructive_sleep_apnea_does_not_affect_the_recurrence_of_atrial_fibrillation_ L2 - https://doi.org/10.1111/j.1540-8159.2006.00426.x DB - PRIME DP - Unbound Medicine ER -