TY - JOUR T1 - Collaborative trial validation study of two methods, one based on high performance liquid chromatography-tandem mass spectrometry and on gas chromatography-mass spectrometry for the determination of acrylamide in bakery and potato products. AU - Wenzl,Thomas, AU - Karasek,Lubomir, AU - Rosen,Johan, AU - Hellenaes,Karl-Erik, AU - Crews,Colin, AU - Castle,Laurence, AU - Anklam,Elke, Y1 - 2006/08/08/ PY - 2006/05/22/received PY - 2006/07/03/revised PY - 2006/07/06/accepted PY - 2006/8/11/pubmed PY - 2006/12/16/medline PY - 2006/8/11/entrez SP - 211 EP - 8 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1132 IS - 1-2 N2 - A European inter-laboratory study was conducted to validate two analytical procedures for the determination of acrylamide in bakery ware (crispbreads, biscuits) and potato products (chips), within a concentration range from about 20 microg/kg to about 9000 microgg/kg. The methods are based on gas chromatography-mass spectrometry (GC-MS) of the derivatised analyte and on high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) of native acrylamide. Isotope dilution with isotopically labelled acrylamide was an integral part of both methods. The study was evaluated according to internationally accepted guidelines. The performance of the HPLC-MS/MS method was found to be superior to that of the GC-MS method and to be fit-for-the-purpose. SN - 0021-9673 UR - https://www.unboundmedicine.com/medline/citation/16899249/Collaborative_trial_validation_study_of_two_methods_one_based_on_high_performance_liquid_chromatography_tandem_mass_spectrometry_and_on_gas_chromatography_mass_spectrometry_for_the_determination_of_acrylamide_in_bakery_and_potato_products_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9673(06)01341-0 DB - PRIME DP - Unbound Medicine ER -