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[The use of angiotensin converting enzyme (ACE) inhibitors during pregnancy clearly increases the risk of congenital malformations].
Ned Tijdschr Geneeskd 2006; 150(29):1605-7NT

Abstract

Recently, an important study was published concerning the possible teratogenic effects of angiotensin converting enzyme (ACE) inhibitors. Non-diabetic women who had used an ACE inhibitor during the first trimester of pregnancy had a significantly greater chance of giving birth to an infant with congenital malformations than women who had used no or other antihypertensive agents. The excess risk remained even after adjusting for several potential confounders. The results indicate that ACE inhibitors should not be prescribed to women who are likely to become pregnant during the course of treatment.

Authors+Show Affiliations

Academisch Ziekenhuis Maastricht, afd. Interne Geneeskunde, Postbus 5800, 6202 AZ Maastricht. p.deleeuw@intmed.unimaas.nl

Pub Type(s)

English Abstract
Journal Article

Language

dut

PubMed ID

16901062

Citation

de Leeuw, P W.. "[The Use of Angiotensin Converting Enzyme (ACE) Inhibitors During Pregnancy Clearly Increases the Risk of Congenital Malformations]." Nederlands Tijdschrift Voor Geneeskunde, vol. 150, no. 29, 2006, pp. 1605-7.
de Leeuw PW. [The use of angiotensin converting enzyme (ACE) inhibitors during pregnancy clearly increases the risk of congenital malformations]. Ned Tijdschr Geneeskd. 2006;150(29):1605-7.
de Leeuw, P. W. (2006). [The use of angiotensin converting enzyme (ACE) inhibitors during pregnancy clearly increases the risk of congenital malformations]. Nederlands Tijdschrift Voor Geneeskunde, 150(29), pp. 1605-7.
de Leeuw PW. [The Use of Angiotensin Converting Enzyme (ACE) Inhibitors During Pregnancy Clearly Increases the Risk of Congenital Malformations]. Ned Tijdschr Geneeskd. 2006 Jul 22;150(29):1605-7. PubMed PMID: 16901062.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The use of angiotensin converting enzyme (ACE) inhibitors during pregnancy clearly increases the risk of congenital malformations]. A1 - de Leeuw,P W, PY - 2006/8/12/pubmed PY - 2006/9/1/medline PY - 2006/8/12/entrez SP - 1605 EP - 7 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 150 IS - 29 N2 - Recently, an important study was published concerning the possible teratogenic effects of angiotensin converting enzyme (ACE) inhibitors. Non-diabetic women who had used an ACE inhibitor during the first trimester of pregnancy had a significantly greater chance of giving birth to an infant with congenital malformations than women who had used no or other antihypertensive agents. The excess risk remained even after adjusting for several potential confounders. The results indicate that ACE inhibitors should not be prescribed to women who are likely to become pregnant during the course of treatment. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/16901062/[The_use_of_angiotensin_converting_enzyme__ACE__inhibitors_during_pregnancy_clearly_increases_the_risk_of_congenital_malformations]_ L2 - http://www.diseaseinfosearch.org/result/5922 DB - PRIME DP - Unbound Medicine ER -