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The compatibility of a nucleopolyhedrosis virus control with resistance management for Bacillus thuringiensis: co-infection and cross-resistance studies with the diamondback moth, Plutella xylostella.
J Invertebr Pathol. 2006 Oct; 93(2):114-20.JI

Abstract

The use of genetically modified crops expressing Bacillus thuringiensis (Bt) toxins can lead to the reduction in application of broad-spectrum pesticides and an increased opportunity for supplementary biological control. Bt microbial sprays are also used by organic growers or as part of integrated pest management programs that rely on the use of natural enemies. In both applications the evolution of resistance to Bt toxins is a potential problem. Natural enemies (pathogens or insects) acting in combination with toxins can accelerate or decelerate the evolution of resistance to Bt. In the present study we investigated whether the use of a nucleopolyhedrovirus (AcMNPV) could potentially affect the evolution of resistance to the Bt toxin Cry1Ac in Plutella xylostella. At low toxin doses there was evidence for antagonistic interactions between AcMNPV and Cry1Ac resistant and susceptible insects. However, this antagonism was much stronger and more widespread for susceptible larvae; interactions were generally not distinguishable from additive for resistant larvae. Selection for resistance to Cry1Ac in two populations of P. xylostella with differing resistance mechanisms did not produce any correlated changes in resistance to AcMNPV. Stronger antagonistic interactions between Bt and AcMNPV on susceptible rather than resistant larvae can decrease the relative fitness between Bt-resistant and susceptible larvae. These interactions and the lack of cross-resistance between virus and toxin suggest that the use of NPV is compatible with resistance management to Bt products.

Authors+Show Affiliations

Raymond B
Division of Biology, Faculty of Life Sciences, Imperial College London, Silwood Park campus, Ascot, BERKS, SL5 7PY, UK. benjamin.raymond@zoo.ox.ac.uk <benjamin.raymond@zoo.ox.ac.uk>
Sayyed AH
No affiliation info available
Wright DJ
No affiliation info available

MeSH

AnimalsBacillus thuringiensisBacillus thuringiensis ToxinsBacterial ProteinsBacterial ToxinsDNA Virus InfectionsDisease SusceptibilityDrug ResistanceEndotoxinsGram-Positive Bacterial InfectionsHemolysin ProteinsImmunity, InnateInsecticide ResistanceInsecticidesLarvaMothsNucleopolyhedrovirusesPest Control, Biological

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16905146

Citation

Raymond, B, et al. "The Compatibility of a Nucleopolyhedrosis Virus Control With Resistance Management for Bacillus Thuringiensis: Co-infection and Cross-resistance Studies With the Diamondback Moth, Plutella Xylostella." Journal of Invertebrate Pathology, vol. 93, no. 2, 2006, pp. 114-20.
Raymond B, Sayyed AH, Wright DJ. The compatibility of a nucleopolyhedrosis virus control with resistance management for Bacillus thuringiensis: co-infection and cross-resistance studies with the diamondback moth, Plutella xylostella. J Invertebr Pathol. 2006;93(2):114-20.
Raymond, B., Sayyed, A. H., & Wright, D. J. (2006). The compatibility of a nucleopolyhedrosis virus control with resistance management for Bacillus thuringiensis: co-infection and cross-resistance studies with the diamondback moth, Plutella xylostella. Journal of Invertebrate Pathology, 93(2), 114-20.
Raymond B, Sayyed AH, Wright DJ. The Compatibility of a Nucleopolyhedrosis Virus Control With Resistance Management for Bacillus Thuringiensis: Co-infection and Cross-resistance Studies With the Diamondback Moth, Plutella Xylostella. J Invertebr Pathol. 2006;93(2):114-20. PubMed PMID: 16905146.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The compatibility of a nucleopolyhedrosis virus control with resistance management for Bacillus thuringiensis: co-infection and cross-resistance studies with the diamondback moth, Plutella xylostella. AU - Raymond,B, AU - Sayyed,A H, AU - Wright,D J, Y1 - 2006/08/14/ PY - 2006/03/03/received PY - 2006/06/19/revised PY - 2006/06/26/accepted PY - 2006/8/15/pubmed PY - 2006/12/9/medline PY - 2006/8/15/entrez SP - 114 EP - 20 JF - Journal of invertebrate pathology JO - J Invertebr Pathol VL - 93 IS - 2 N2 - The use of genetically modified crops expressing Bacillus thuringiensis (Bt) toxins can lead to the reduction in application of broad-spectrum pesticides and an increased opportunity for supplementary biological control. Bt microbial sprays are also used by organic growers or as part of integrated pest management programs that rely on the use of natural enemies. In both applications the evolution of resistance to Bt toxins is a potential problem. Natural enemies (pathogens or insects) acting in combination with toxins can accelerate or decelerate the evolution of resistance to Bt. In the present study we investigated whether the use of a nucleopolyhedrovirus (AcMNPV) could potentially affect the evolution of resistance to the Bt toxin Cry1Ac in Plutella xylostella. At low toxin doses there was evidence for antagonistic interactions between AcMNPV and Cry1Ac resistant and susceptible insects. However, this antagonism was much stronger and more widespread for susceptible larvae; interactions were generally not distinguishable from additive for resistant larvae. Selection for resistance to Cry1Ac in two populations of P. xylostella with differing resistance mechanisms did not produce any correlated changes in resistance to AcMNPV. Stronger antagonistic interactions between Bt and AcMNPV on susceptible rather than resistant larvae can decrease the relative fitness between Bt-resistant and susceptible larvae. These interactions and the lack of cross-resistance between virus and toxin suggest that the use of NPV is compatible with resistance management to Bt products. SN - 0022-2011 UR - https://www.unboundmedicine.com/medline/citation/16905146/The_compatibility_of_a_nucleopolyhedrosis_virus_control_with_resistance_management_for_Bacillus_thuringiensis:_co_infection_and_cross_resistance_studies_with_the_diamondback_moth_Plutella_xylostella_ DB - PRIME DP - Unbound Medicine ER -