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Psychiatric comorbidity is associated with drug use and HIV risk in syringe exchange participants.
J Nerv Ment Dis. 2006 Aug; 194(8):577-83.JN

Abstract

The present study evaluated the effects of psychiatric comorbidity on substance use disorder prevalence, HIV risk behavior, and other problem severity in male and female out-of-treatment injection drug users newly registered at a syringe exchange program. Participants (N = 338) were administered the Structured Clinical Interview for the DSM-IV, the Addiction Severity Index, and the Risk Assessment Battery, and classified into one of four diagnostic groups: (1) no antisocial personality disorder (APD) or Axis I psychiatric disorder (N = 162), (2) APD only (N = 74), (3) Axis I psychiatric disorder only (N = 55), or (4) APD plus Axis I psychiatric disorder (N = 47). Psychiatric comorbidity was associated with higher rates of substance use disorder and more HIV risk and other problem severity. In general, participants with both APD and an Axis I disorder exhibited the most problem severity. APD was uniquely associated with higher prevalence for each substance use disorder assessed in this study and with elevated HIV risk. These results support and extend studies conducted with opioid-dependent individuals recruited from treatment and community settings, and reinforce the need to develop interventions to encourage syringe exchange program participants to enroll in treatment.

Authors+Show Affiliations

Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, Maryland, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

16909065

Citation

Disney, Elizabeth, et al. "Psychiatric Comorbidity Is Associated With Drug Use and HIV Risk in Syringe Exchange Participants." The Journal of Nervous and Mental Disease, vol. 194, no. 8, 2006, pp. 577-83.
Disney E, Kidorf M, Kolodner K, et al. Psychiatric comorbidity is associated with drug use and HIV risk in syringe exchange participants. J Nerv Ment Dis. 2006;194(8):577-83.
Disney, E., Kidorf, M., Kolodner, K., King, V., Peirce, J., Beilenson, P., & Brooner, R. K. (2006). Psychiatric comorbidity is associated with drug use and HIV risk in syringe exchange participants. The Journal of Nervous and Mental Disease, 194(8), 577-83.
Disney E, et al. Psychiatric Comorbidity Is Associated With Drug Use and HIV Risk in Syringe Exchange Participants. J Nerv Ment Dis. 2006;194(8):577-83. PubMed PMID: 16909065.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Psychiatric comorbidity is associated with drug use and HIV risk in syringe exchange participants. AU - Disney,Elizabeth, AU - Kidorf,Michael, AU - Kolodner,Ken, AU - King,Van, AU - Peirce,Jessica, AU - Beilenson,Peter, AU - Brooner,Robert K, PY - 2006/8/16/pubmed PY - 2006/9/12/medline PY - 2006/8/16/entrez SP - 577 EP - 83 JF - The Journal of nervous and mental disease JO - J Nerv Ment Dis VL - 194 IS - 8 N2 - The present study evaluated the effects of psychiatric comorbidity on substance use disorder prevalence, HIV risk behavior, and other problem severity in male and female out-of-treatment injection drug users newly registered at a syringe exchange program. Participants (N = 338) were administered the Structured Clinical Interview for the DSM-IV, the Addiction Severity Index, and the Risk Assessment Battery, and classified into one of four diagnostic groups: (1) no antisocial personality disorder (APD) or Axis I psychiatric disorder (N = 162), (2) APD only (N = 74), (3) Axis I psychiatric disorder only (N = 55), or (4) APD plus Axis I psychiatric disorder (N = 47). Psychiatric comorbidity was associated with higher rates of substance use disorder and more HIV risk and other problem severity. In general, participants with both APD and an Axis I disorder exhibited the most problem severity. APD was uniquely associated with higher prevalence for each substance use disorder assessed in this study and with elevated HIV risk. These results support and extend studies conducted with opioid-dependent individuals recruited from treatment and community settings, and reinforce the need to develop interventions to encourage syringe exchange program participants to enroll in treatment. SN - 0022-3018 UR - https://www.unboundmedicine.com/medline/citation/16909065/Psychiatric_comorbidity_is_associated_with_drug_use_and_HIV_risk_in_syringe_exchange_participants_ L2 - https://doi.org/10.1097/01.nmd.0000230396.17230.28 DB - PRIME DP - Unbound Medicine ER -