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Thoughts on B-vitamins and dementia.

Abstract

The B-vitamins, including vitamins B12, B6, B1, B2, niacin (B3) and folate (B9), have been implicated as protective risk factors against cognitive decline and Alzheimer's disease. This commentary reviews the evidence to support protective relations of these vitamins, including consideration of known vitamin deficiency syndromes, theories of underlying biologic mechanisms, and the epidemiologic evidence. We also comment on the potential benefits and harms of vitamin supplementation as well as make recommendations for the direction of future studies.

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  • Authors+Show Affiliations

    ,

    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA. Martha.C.morris@rush.edu

    ,

    Source

    MeSH

    Alzheimer Disease
    Dementia
    Folic Acid
    Humans
    Risk Factors
    Vitamin B Complex

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    16917152

    Citation

    Morris, Martha Clare, et al. "Thoughts On B-vitamins and Dementia." Journal of Alzheimer's Disease : JAD, vol. 9, no. 4, 2006, pp. 429-33.
    Morris MC, Schneider JA, Tangney CC. Thoughts on B-vitamins and dementia. J Alzheimers Dis. 2006;9(4):429-33.
    Morris, M. C., Schneider, J. A., & Tangney, C. C. (2006). Thoughts on B-vitamins and dementia. Journal of Alzheimer's Disease : JAD, 9(4), pp. 429-33.
    Morris MC, Schneider JA, Tangney CC. Thoughts On B-vitamins and Dementia. J Alzheimers Dis. 2006;9(4):429-33. PubMed PMID: 16917152.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Thoughts on B-vitamins and dementia. AU - Morris,Martha Clare, AU - Schneider,Julie A, AU - Tangney,Christine C, PY - 2006/8/19/pubmed PY - 2006/11/1/medline PY - 2006/8/19/entrez SP - 429 EP - 33 JF - Journal of Alzheimer's disease : JAD JO - J. Alzheimers Dis. VL - 9 IS - 4 N2 - The B-vitamins, including vitamins B12, B6, B1, B2, niacin (B3) and folate (B9), have been implicated as protective risk factors against cognitive decline and Alzheimer's disease. This commentary reviews the evidence to support protective relations of these vitamins, including consideration of known vitamin deficiency syndromes, theories of underlying biologic mechanisms, and the epidemiologic evidence. We also comment on the potential benefits and harms of vitamin supplementation as well as make recommendations for the direction of future studies. SN - 1387-2877 UR - https://www.unboundmedicine.com/medline/citation/16917152/Thoughts_on_B_vitamins_and_dementia_ L2 - https://content.iospress.com/openurl?genre=article&issn=1387-2877&volume=9&issue=4&spage=429 DB - PRIME DP - Unbound Medicine ER -