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Long-term risks for thyroid cancer and other neoplasms after exposure to radiation.

Abstract

Radiation-related thyroid cancer continues to be a clinical concern for two reasons: the risks associated with the widespread use of radiation treatments for benign conditions in the middle of the last century persist for decades after exposure; and radiation continues to be an effective component of the treatment of several childhood malignancies. Patients who were irradiated in the head and neck area need to be evaluated for thyroid cancer, benign thyroid nodules, hyperparathyroidism, salivary-gland neoplasms and neural tumors, including acoustic neuromas. Radiation-related thyroid cancers appear to have the same clinical behavior as other thyroid cancers, but many irradiated patients are entering the age range when more aggressive neoplasms occur. In this paper, we review how to approach the clinical management of a patient with a history of radiation exposure in the thyroid area, and how to treat radiation-exposed patients who develop related neoplasms, especially thyroid cancer.

Authors+Show Affiliations

Section of Endocrinology and Metabolism, University of Illinois College of Medicine, Chicago 60612, USA. abschnei@uic.eduNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16929376

Citation

Schneider, Arthur B., and David H. Sarne. "Long-term Risks for Thyroid Cancer and Other Neoplasms After Exposure to Radiation." Nature Clinical Practice. Endocrinology & Metabolism, vol. 1, no. 2, 2005, pp. 82-91.
Schneider AB, Sarne DH. Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. Nat Clin Pract Endocrinol Metab. 2005;1(2):82-91.
Schneider, A. B., & Sarne, D. H. (2005). Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. Nature Clinical Practice. Endocrinology & Metabolism, 1(2), pp. 82-91.
Schneider AB, Sarne DH. Long-term Risks for Thyroid Cancer and Other Neoplasms After Exposure to Radiation. Nat Clin Pract Endocrinol Metab. 2005;1(2):82-91. PubMed PMID: 16929376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. AU - Schneider,Arthur B, AU - Sarne,David H, PY - 2005/06/30/received PY - 2005/08/31/accepted PY - 2006/8/25/pubmed PY - 2006/10/26/medline PY - 2006/8/25/entrez SP - 82 EP - 91 JF - Nature clinical practice. Endocrinology & metabolism JO - Nat Clin Pract Endocrinol Metab VL - 1 IS - 2 N2 - Radiation-related thyroid cancer continues to be a clinical concern for two reasons: the risks associated with the widespread use of radiation treatments for benign conditions in the middle of the last century persist for decades after exposure; and radiation continues to be an effective component of the treatment of several childhood malignancies. Patients who were irradiated in the head and neck area need to be evaluated for thyroid cancer, benign thyroid nodules, hyperparathyroidism, salivary-gland neoplasms and neural tumors, including acoustic neuromas. Radiation-related thyroid cancers appear to have the same clinical behavior as other thyroid cancers, but many irradiated patients are entering the age range when more aggressive neoplasms occur. In this paper, we review how to approach the clinical management of a patient with a history of radiation exposure in the thyroid area, and how to treat radiation-exposed patients who develop related neoplasms, especially thyroid cancer. SN - 1745-8366 UR - http://www.unboundmedicine.com/medline/citation/16929376/full_citation L2 - http://dx.doi.org/10.1038/ncpendmet0022 DB - PRIME DP - Unbound Medicine ER -