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Morphologic and morphometric magnetic resonance imaging features of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy.
Am J Vet Res. 2006 Sep; 67(9):1601-12.AJ

Abstract

OBJECTIVE

To compare morphologic and morphometric features of the cervical vertebral column and spinal cord of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy (CSM; wobbler syndrome) detected via magnetic resonance imaging (MRI).

ANIMALS

16 clinically normal and 16 CSM-affected Doberman Pinschers.

PROCEDURES

For each dog, MRI of the cervical vertebral column (in neutral and traction positions) was performed. Morphologically, MRI abnormalities were classified according to a spinal cord compression scale. Foraminal stenosis and intervertebral disk degeneration and protrusion were also recorded. Morphometric measurements of the vertebral canal and spinal cord were obtained in sagittal and transverse MRI planes.

RESULTS

4 of 16 clinically normal and 15 of 16 CSM-affected dogs had spinal cord compression. Twelve clinically normal and all CSM-affected dogs had disk degeneration. Foraminal stenosis was detected in 11 clinically normal and 14 CSM-affected dogs. Vertebral canal and spinal cord areas were consistently smaller in CSM-affected dogs, compared with clinically normal dogs. In neutral and traction positions, the intervertebral disks of CSM-affected dogs were wider than those of clinically normal dogs but the amount of disk distraction was similar between groups.

CONCLUSIONS AND CLINICAL RELEVANCE

The incidence of intervertebral disk degeneration and foraminal stenosis in clinically normal Doberman Pinschers was high; cervical spinal cord compression may be present without concurrent clinical signs. A combination of static factors (ie, a relatively stenotic vertebral canal and wider intervertebral disks) distinguished CSM-affected dogs from clinically normal dogs and appears to be a key feature in the pathogenesis of CSM.

Authors+Show Affiliations

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16948609

Citation

da Costa, Ronaldo C., et al. "Morphologic and Morphometric Magnetic Resonance Imaging Features of Doberman Pinschers With and Without Clinical Signs of Cervical Spondylomyelopathy." American Journal of Veterinary Research, vol. 67, no. 9, 2006, pp. 1601-12.
da Costa RC, Parent JM, Partlow G, et al. Morphologic and morphometric magnetic resonance imaging features of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy. Am J Vet Res. 2006;67(9):1601-12.
da Costa, R. C., Parent, J. M., Partlow, G., Dobson, H., Holmberg, D. L., & Lamarre, J. (2006). Morphologic and morphometric magnetic resonance imaging features of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy. American Journal of Veterinary Research, 67(9), 1601-12.
da Costa RC, et al. Morphologic and Morphometric Magnetic Resonance Imaging Features of Doberman Pinschers With and Without Clinical Signs of Cervical Spondylomyelopathy. Am J Vet Res. 2006;67(9):1601-12. PubMed PMID: 16948609.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Morphologic and morphometric magnetic resonance imaging features of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy. AU - da Costa,Ronaldo C, AU - Parent,Joane M, AU - Partlow,Gary, AU - Dobson,Howard, AU - Holmberg,David L, AU - Lamarre,Jonathan, PY - 2006/9/5/pubmed PY - 2006/10/18/medline PY - 2006/9/5/entrez SP - 1601 EP - 12 JF - American journal of veterinary research JO - Am. J. Vet. Res. VL - 67 IS - 9 N2 - OBJECTIVE: To compare morphologic and morphometric features of the cervical vertebral column and spinal cord of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy (CSM; wobbler syndrome) detected via magnetic resonance imaging (MRI). ANIMALS: 16 clinically normal and 16 CSM-affected Doberman Pinschers. PROCEDURES: For each dog, MRI of the cervical vertebral column (in neutral and traction positions) was performed. Morphologically, MRI abnormalities were classified according to a spinal cord compression scale. Foraminal stenosis and intervertebral disk degeneration and protrusion were also recorded. Morphometric measurements of the vertebral canal and spinal cord were obtained in sagittal and transverse MRI planes. RESULTS: 4 of 16 clinically normal and 15 of 16 CSM-affected dogs had spinal cord compression. Twelve clinically normal and all CSM-affected dogs had disk degeneration. Foraminal stenosis was detected in 11 clinically normal and 14 CSM-affected dogs. Vertebral canal and spinal cord areas were consistently smaller in CSM-affected dogs, compared with clinically normal dogs. In neutral and traction positions, the intervertebral disks of CSM-affected dogs were wider than those of clinically normal dogs but the amount of disk distraction was similar between groups. CONCLUSIONS AND CLINICAL RELEVANCE: The incidence of intervertebral disk degeneration and foraminal stenosis in clinically normal Doberman Pinschers was high; cervical spinal cord compression may be present without concurrent clinical signs. A combination of static factors (ie, a relatively stenotic vertebral canal and wider intervertebral disks) distinguished CSM-affected dogs from clinically normal dogs and appears to be a key feature in the pathogenesis of CSM. SN - 0002-9645 UR - https://www.unboundmedicine.com/medline/citation/16948609/Morphologic_and_morphometric_magnetic_resonance_imaging_features_of_Doberman_Pinschers_with_and_without_clinical_signs_of_cervical_spondylomyelopathy_ L2 - http://avmajournals.avma.org/doi/full/10.2460/ajvr.67.9.1601?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -