Tags

Type your tag names separated by a space and hit enter

Antibacterial activity of crude methanolic extract and its fractions of aerial parts of Anthemis tinctoria.
Indian J Biochem Biophys. 2005 Dec; 42(6):395-7.IJ

Abstract

The antibacterial activity of the methanolic extract and its fractions of aerial parts of Aniheinis tinctoria (Asteraceae) was investigated against representative gram-positive Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 29212) and gram-negative strains Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). The activity was concentrated mainly in the dichloromethane (DCM) and hexane fractions of crude methanolic extract. The 5 mg of DCM extract per disk produced 15-16 mm of inhibition zone against S. aureus and P. aeruginosa, however, no activity was found against E. faecalis and E. coli. The hexane fraction showed activity against S. aureus, P. aeruginosa and E. faecalis. As DCM fraction showed the highest antibacterial activity in the disk diffusion assay, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of only this fraction was determined against S. aureus and P. aeruginosa. These values were found to be in the range of 1.25 to 10 mg/ml.

Authors+Show Affiliations

Canakkale Onsekiz Mart University, Faculty of Arts & Sciences, Department of Chemistry, Turkey. cahitakgul@comu.edu.trNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16955742

Citation

Akgul, Cahit, and Gulsen Saglikoglu. "Antibacterial Activity of Crude Methanolic Extract and Its Fractions of Aerial Parts of Anthemis Tinctoria." Indian Journal of Biochemistry & Biophysics, vol. 42, no. 6, 2005, pp. 395-7.
Akgul C, Saglikoglu G. Antibacterial activity of crude methanolic extract and its fractions of aerial parts of Anthemis tinctoria. Indian J Biochem Biophys. 2005;42(6):395-7.
Akgul, C., & Saglikoglu, G. (2005). Antibacterial activity of crude methanolic extract and its fractions of aerial parts of Anthemis tinctoria. Indian Journal of Biochemistry & Biophysics, 42(6), 395-7.
Akgul C, Saglikoglu G. Antibacterial Activity of Crude Methanolic Extract and Its Fractions of Aerial Parts of Anthemis Tinctoria. Indian J Biochem Biophys. 2005;42(6):395-7. PubMed PMID: 16955742.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibacterial activity of crude methanolic extract and its fractions of aerial parts of Anthemis tinctoria. AU - Akgul,Cahit, AU - Saglikoglu,Gulsen, PY - 2006/9/8/pubmed PY - 2006/10/4/medline PY - 2006/9/8/entrez SP - 395 EP - 7 JF - Indian journal of biochemistry & biophysics JO - Indian J. Biochem. Biophys. VL - 42 IS - 6 N2 - The antibacterial activity of the methanolic extract and its fractions of aerial parts of Aniheinis tinctoria (Asteraceae) was investigated against representative gram-positive Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 29212) and gram-negative strains Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). The activity was concentrated mainly in the dichloromethane (DCM) and hexane fractions of crude methanolic extract. The 5 mg of DCM extract per disk produced 15-16 mm of inhibition zone against S. aureus and P. aeruginosa, however, no activity was found against E. faecalis and E. coli. The hexane fraction showed activity against S. aureus, P. aeruginosa and E. faecalis. As DCM fraction showed the highest antibacterial activity in the disk diffusion assay, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of only this fraction was determined against S. aureus and P. aeruginosa. These values were found to be in the range of 1.25 to 10 mg/ml. SN - 0301-1208 UR - https://www.unboundmedicine.com/medline/citation/16955742/Antibacterial_activity_of_crude_methanolic_extract_and_its_fractions_of_aerial_parts_of_Anthemis_tinctoria_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -