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Correlation between results of head-up tilt test and clinical features in patients with syncope or presyncope.
J Electrocardiol. 2007 Apr; 40(2):200-2.JE

Abstract

BACKGROUND

Head-up tilt test (HUTT) is a well-established diagnostic tool in patients with suspected vasovagal syncope. Identification of factors that predict a positive HUTT result could simplify diagnostic steps. The aim of this study was to assess the correlation between clinical characteristics of patients with suspected neurocardiogenic syncope or presyncope and results of HUTT.

MATERIALS AND METHODS

The study group consisted of 90 patients (55 men, 35 women; mean age, 43.2 +/- 17 years) with a history of syncope or presyncope. Cardiological and neurologic test findings were normal in every patient. The patients were tilted to a 70 degrees position for 45 minutes. If the first phase produced a negative response, the patients received 400 mug of sublingual nitroglycerin for the second phase and continued to be tilted for an additional 15 minutes.

RESULTS

Sixty-four patients had a positive HUTT result, characterized by a vasodepressive response in 26 patients, mixed response in 24 patients, and cardioinhibitory response in 14 patients. In logistic regression analysis, the presence of prodromal symptoms was a predictor of a positive HUTT result (P = .002).

CONCLUSION

We showed that the prognostic performance of clinical features, including the time interval between the last episode and HUTT, the number of syncope or presyncope episodes, age, and sex, was not ideal. The presence of prodromal symptoms might be more likely to predict a positive response during HUTT.

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Authors+Show Affiliations

Emkanjoo Z
Department of Pacemaker and Electrophysiology, Rajaie Cardiovascular Medical Center, Tehran, Iran. emkanjoo@rhc.ac.ir
Alizadeh A
No affiliation info available
Alasti M
No affiliation info available
Fadaie AA
No affiliation info available
Haghjoo M
No affiliation info available
Fazelifar AF
No affiliation info available
Sadr-Ameli MA
No affiliation info available

MeSH

AdultElectrocardiographyFemaleHumansMalePrognosisReproducibility of ResultsSensitivity and SpecificitySyncope, VasovagalTilt-Table Test

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16963069

Citation

Emkanjoo, Zahra, et al. "Correlation Between Results of Head-up Tilt Test and Clinical Features in Patients With Syncope or Presyncope." Journal of Electrocardiology, vol. 40, no. 2, 2007, pp. 200-2.
Emkanjoo Z, Alizadeh A, Alasti M, et al. Correlation between results of head-up tilt test and clinical features in patients with syncope or presyncope. J Electrocardiol. 2007;40(2):200-2.
Emkanjoo, Z., Alizadeh, A., Alasti, M., Fadaie, A. A., Haghjoo, M., Fazelifar, A. F., & Sadr-Ameli, M. A. (2007). Correlation between results of head-up tilt test and clinical features in patients with syncope or presyncope. Journal of Electrocardiology, 40(2), 200-2.
Emkanjoo Z, et al. Correlation Between Results of Head-up Tilt Test and Clinical Features in Patients With Syncope or Presyncope. J Electrocardiol. 2007;40(2):200-2. PubMed PMID: 16963069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation between results of head-up tilt test and clinical features in patients with syncope or presyncope. AU - Emkanjoo,Zahra, AU - Alizadeh,Abolfath, AU - Alasti,Mohammad, AU - Fadaie,Ali Asghar, AU - Haghjoo,Majid, AU - Fazelifar,Amir Farjam, AU - Sadr-Ameli,Mohammad Ali, Y1 - 2006/09/11/ PY - 2006/04/03/received PY - 2006/07/12/accepted PY - 2006/9/12/pubmed PY - 2007/4/4/medline PY - 2006/9/12/entrez SP - 200 EP - 2 JF - Journal of electrocardiology JO - J Electrocardiol VL - 40 IS - 2 N2 - BACKGROUND: Head-up tilt test (HUTT) is a well-established diagnostic tool in patients with suspected vasovagal syncope. Identification of factors that predict a positive HUTT result could simplify diagnostic steps. The aim of this study was to assess the correlation between clinical characteristics of patients with suspected neurocardiogenic syncope or presyncope and results of HUTT. MATERIALS AND METHODS: The study group consisted of 90 patients (55 men, 35 women; mean age, 43.2 +/- 17 years) with a history of syncope or presyncope. Cardiological and neurologic test findings were normal in every patient. The patients were tilted to a 70 degrees position for 45 minutes. If the first phase produced a negative response, the patients received 400 mug of sublingual nitroglycerin for the second phase and continued to be tilted for an additional 15 minutes. RESULTS: Sixty-four patients had a positive HUTT result, characterized by a vasodepressive response in 26 patients, mixed response in 24 patients, and cardioinhibitory response in 14 patients. In logistic regression analysis, the presence of prodromal symptoms was a predictor of a positive HUTT result (P = .002). CONCLUSION: We showed that the prognostic performance of clinical features, including the time interval between the last episode and HUTT, the number of syncope or presyncope episodes, age, and sex, was not ideal. The presence of prodromal symptoms might be more likely to predict a positive response during HUTT. SN - 1532-8430 UR - https://www.unboundmedicine.com/medline/citation/16963069/Correlation_between_results_of_head_up_tilt_test_and_clinical_features_in_patients_with_syncope_or_presyncope_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-0736(06)00150-6 DB - PRIME DP - Unbound Medicine ER -