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Estimation of adenosine triphosphate utilization of rat mast cells during and after anaphylactic histamine secretion.
FEBS Lett. 1990 Jul 30; 268(1):103-6.FL

Abstract

Determination of the cellular content of adenosine triphosphate (ATP) and the rate of ATP-synthesis were used to estimate the cellular utilization of ATP in relation to anaphylactic histamine secretion. There was an increased rate of oxidative ATP-synthesis and a decreased cellular ATP content during the time period of histamine secretion and immediately after its completion. During secretion the additional ATP-utilization above the basal level of ATP-synthesis was 0.51 pmol/10(3) cells. 2.5 min after cell activation, the rate of additional ATP-utilization was 0.30 pmol/10(3) cells/min, and the persistent ATP-decrease observed after 30 and 120 min may be due to a decreased rate of oxidative ATP-synthesis.

Authors+Show Affiliations

Johansen T
Department of Pharmacology, Medical School, Odense University, Denmark.

MeSH

Adenosine TriphosphateAnaphylaxisAnimalsAntimycin ADeoxyglucoseEnergy MetabolismExocytosisHistamine ReleaseIn Vitro TechniquesMaleMast CellsOligomycinsRatsRats, Inbred Strains

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1696546

Citation

Johansen, T. "Estimation of Adenosine Triphosphate Utilization of Rat Mast Cells During and After Anaphylactic Histamine Secretion." FEBS Letters, vol. 268, no. 1, 1990, pp. 103-6.
Johansen T. Estimation of adenosine triphosphate utilization of rat mast cells during and after anaphylactic histamine secretion. FEBS Lett. 1990;268(1):103-6.
Johansen, T. (1990). Estimation of adenosine triphosphate utilization of rat mast cells during and after anaphylactic histamine secretion. FEBS Letters, 268(1), 103-6.
Johansen T. Estimation of Adenosine Triphosphate Utilization of Rat Mast Cells During and After Anaphylactic Histamine Secretion. FEBS Lett. 1990 Jul 30;268(1):103-6. PubMed PMID: 1696546.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Estimation of adenosine triphosphate utilization of rat mast cells during and after anaphylactic histamine secretion. A1 - Johansen,T, PY - 1990/7/30/pubmed PY - 1990/7/30/medline PY - 1990/7/30/entrez SP - 103 EP - 6 JF - FEBS letters JO - FEBS Lett VL - 268 IS - 1 N2 - Determination of the cellular content of adenosine triphosphate (ATP) and the rate of ATP-synthesis were used to estimate the cellular utilization of ATP in relation to anaphylactic histamine secretion. There was an increased rate of oxidative ATP-synthesis and a decreased cellular ATP content during the time period of histamine secretion and immediately after its completion. During secretion the additional ATP-utilization above the basal level of ATP-synthesis was 0.51 pmol/10(3) cells. 2.5 min after cell activation, the rate of additional ATP-utilization was 0.30 pmol/10(3) cells/min, and the persistent ATP-decrease observed after 30 and 120 min may be due to a decreased rate of oxidative ATP-synthesis. SN - 0014-5793 UR - https://www.unboundmedicine.com/medline/citation/1696546/Estimation_of_adenosine_triphosphate_utilization_of_rat_mast_cells_during_and_after_anaphylactic_histamine_secretion_ DB - PRIME DP - Unbound Medicine ER -