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Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma.
Acta Ophthalmol Scand. 2006 Oct; 84(5):650-5.AO

Abstract

PURPOSE

To compare the abilities of scanning laser polarimetry with the variable corneal compensator (GDx VCC) with those of optical coherence tomography (Stratus OCT) in discriminating between healthy and early-to-moderate perimetric glaucomatous eyes.

METHODS

A total of 95 glaucomatous patients (mean deviation - 3.7 +/- 3.0 dB, pattern standard deviation 4.5 +/- 2.7 dB) and 62 control subjects underwent imaging by the GDx VCC and Stratus OCT using both optic nerve head (ONH) and retinal nerve fibre layer (RNFL) scan protocols. One eye per patient was considered. Sensitivity at > or = 90% specificity and area under the receiver operating characteristic curve (AROC) were calculated for each GDx VCC and Stratus OCT index.

RESULTS

The largest AROCs with Stratus OCT were associated with cup : disc area ratio (0.88) for ONH scan indices, and with average thickness (0.84) for RNFL scan indices. The nerve fibre indicator provided the greatest AROC for the GDx VCC indices (0.85).

CONCLUSIONS

Both the GDx VCC and Stratus OCT instruments were shown to be useful in the detection of glaucomatous damage. The best performing indices for the GDx VCC and Stratus OCT with both ONH and RNFL scans gave similar AROCs, showing a moderate sensitivity in early-to-moderate glaucoma patients.

Authors+Show Affiliations

Department of Ophthalmology, Santa Maria della Misericordia Hospital, Udine, Italy. brusini@libero.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16965496

Citation

Brusini, Paolo, et al. "Comparison Between GDx VCC Scanning Laser Polarimetry and Stratus OCT Optical Coherence Tomography in the Diagnosis of Chronic Glaucoma." Acta Ophthalmologica Scandinavica, vol. 84, no. 5, 2006, pp. 650-5.
Brusini P, Salvetat ML, Zeppieri M, et al. Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma. Acta Ophthalmol Scand. 2006;84(5):650-5.
Brusini, P., Salvetat, M. L., Zeppieri, M., Tosoni, C., Parisi, L., & Felletti, M. (2006). Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma. Acta Ophthalmologica Scandinavica, 84(5), 650-5.
Brusini P, et al. Comparison Between GDx VCC Scanning Laser Polarimetry and Stratus OCT Optical Coherence Tomography in the Diagnosis of Chronic Glaucoma. Acta Ophthalmol Scand. 2006;84(5):650-5. PubMed PMID: 16965496.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma. AU - Brusini,Paolo, AU - Salvetat,Maria L, AU - Zeppieri,Marco, AU - Tosoni,Claudia, AU - Parisi,Lucia, AU - Felletti,Mirella, PY - 2006/9/13/pubmed PY - 2006/12/9/medline PY - 2006/9/13/entrez SP - 650 EP - 5 JF - Acta ophthalmologica Scandinavica JO - Acta Ophthalmol Scand VL - 84 IS - 5 N2 - PURPOSE: To compare the abilities of scanning laser polarimetry with the variable corneal compensator (GDx VCC) with those of optical coherence tomography (Stratus OCT) in discriminating between healthy and early-to-moderate perimetric glaucomatous eyes. METHODS: A total of 95 glaucomatous patients (mean deviation - 3.7 +/- 3.0 dB, pattern standard deviation 4.5 +/- 2.7 dB) and 62 control subjects underwent imaging by the GDx VCC and Stratus OCT using both optic nerve head (ONH) and retinal nerve fibre layer (RNFL) scan protocols. One eye per patient was considered. Sensitivity at > or = 90% specificity and area under the receiver operating characteristic curve (AROC) were calculated for each GDx VCC and Stratus OCT index. RESULTS: The largest AROCs with Stratus OCT were associated with cup : disc area ratio (0.88) for ONH scan indices, and with average thickness (0.84) for RNFL scan indices. The nerve fibre indicator provided the greatest AROC for the GDx VCC indices (0.85). CONCLUSIONS: Both the GDx VCC and Stratus OCT instruments were shown to be useful in the detection of glaucomatous damage. The best performing indices for the GDx VCC and Stratus OCT with both ONH and RNFL scans gave similar AROCs, showing a moderate sensitivity in early-to-moderate glaucoma patients. SN - 1395-3907 UR - https://www.unboundmedicine.com/medline/citation/16965496/Comparison_between_GDx_VCC_scanning_laser_polarimetry_and_Stratus_OCT_optical_coherence_tomography_in_the_diagnosis_of_chronic_glaucoma_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1395-3907&date=2006&volume=84&issue=5&spage=650 DB - PRIME DP - Unbound Medicine ER -