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Neurocognitive screening of mercury-exposed children of Andean gold miners.
Int J Occup Environ Health. 2006 Jul-Sep; 12(3):209-14.IJ

Abstract

Performance on Raven's Coloured Progressive Matrices (RCPM) test of visual-spatial reasoning was used to evaluate the effects of mercury (Hg) exposure on 73 Andean children aged 5 to 11 years (mean: 8.4) living in the Nambija and Portovelo gold mining areas of Ecuador, where Hg is widely used in amalgamation. Mean levels of Hg found in blood (Hg(B)), urine (Hg(U)), and hair (Hg(H)) samples were 5.1 microg/L (SD: 2.4; range: 1-10 microg/L), 13.3 microg/L (SD: 25.9; range: 1-166 microg/L), and 8.5 microg/g (SD: 22.8; range: 1-135 microg/g), respectively. Of the children in the Nambija area 67-84.9% had abnormal RCPM standard scores (i.e., < or = 25%tile), depending on the test norm used in the data analysis. Higher standard scores for Peruvian (t = 4.77; p = < 0.0001) and Puerto Rican (t = 4.51; p = < 0.0001) norms than for U.S. norms suggested a linguistic influence. No difference was found between Peruvian and Puerto Rican norms (t = 0.832; p = < 0.408), which showed a significant positive correlation (r = 0.915, p = < 0.0001). Children with abnormal Hg(B) and Hg(H) levels had significantly lower scores on the RCPM subtest B than did children with nontoxic Hg levels (t = -2.16; p = < 0.034). These results suggest that a substantial number of Hg-exposed children in the Nambija study area have neurocognitive deficits in visual-spatial reasoning.

Authors+Show Affiliations

Department of Neurology, Harvard Medical School, The Biological Laboratories, 16 Divinity Avenue, Cambridge, MA 02138, USA. allen_Counter@harvard.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16967826

Citation

Counter, S Allen, et al. "Neurocognitive Screening of Mercury-exposed Children of Andean Gold Miners." International Journal of Occupational and Environmental Health, vol. 12, no. 3, 2006, pp. 209-14.
Counter SA, Buchanan LH, Ortega F. Neurocognitive screening of mercury-exposed children of Andean gold miners. Int J Occup Environ Health. 2006;12(3):209-14.
Counter, S. A., Buchanan, L. H., & Ortega, F. (2006). Neurocognitive screening of mercury-exposed children of Andean gold miners. International Journal of Occupational and Environmental Health, 12(3), 209-14.
Counter SA, Buchanan LH, Ortega F. Neurocognitive Screening of Mercury-exposed Children of Andean Gold Miners. Int J Occup Environ Health. 2006 Jul-Sep;12(3):209-14. PubMed PMID: 16967826.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurocognitive screening of mercury-exposed children of Andean gold miners. AU - Counter,S Allen, AU - Buchanan,Leo H, AU - Ortega,Fernando, PY - 2006/9/14/pubmed PY - 2006/12/9/medline PY - 2006/9/14/entrez SP - 209 EP - 14 JF - International journal of occupational and environmental health JO - Int J Occup Environ Health VL - 12 IS - 3 N2 - Performance on Raven's Coloured Progressive Matrices (RCPM) test of visual-spatial reasoning was used to evaluate the effects of mercury (Hg) exposure on 73 Andean children aged 5 to 11 years (mean: 8.4) living in the Nambija and Portovelo gold mining areas of Ecuador, where Hg is widely used in amalgamation. Mean levels of Hg found in blood (Hg(B)), urine (Hg(U)), and hair (Hg(H)) samples were 5.1 microg/L (SD: 2.4; range: 1-10 microg/L), 13.3 microg/L (SD: 25.9; range: 1-166 microg/L), and 8.5 microg/g (SD: 22.8; range: 1-135 microg/g), respectively. Of the children in the Nambija area 67-84.9% had abnormal RCPM standard scores (i.e., < or = 25%tile), depending on the test norm used in the data analysis. Higher standard scores for Peruvian (t = 4.77; p = < 0.0001) and Puerto Rican (t = 4.51; p = < 0.0001) norms than for U.S. norms suggested a linguistic influence. No difference was found between Peruvian and Puerto Rican norms (t = 0.832; p = < 0.408), which showed a significant positive correlation (r = 0.915, p = < 0.0001). Children with abnormal Hg(B) and Hg(H) levels had significantly lower scores on the RCPM subtest B than did children with nontoxic Hg levels (t = -2.16; p = < 0.034). These results suggest that a substantial number of Hg-exposed children in the Nambija study area have neurocognitive deficits in visual-spatial reasoning. SN - 1077-3525 UR - https://www.unboundmedicine.com/medline/citation/16967826/Neurocognitive_screening_of_mercury_exposed_children_of_Andean_gold_miners_ L2 - https://www.tandfonline.com/doi/full/10.1179/oeh.2006.12.3.209 DB - PRIME DP - Unbound Medicine ER -