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In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst.
Korean J Parasitol 2006; 44(3):239-42KJ

Abstract

To evaluate the protoscolicidal effects of various concentrations of hypertonic glucose, live protoscolices of sheep were exposed to 10%, 15%, 25% and 50% glucose solutions. Cetrimide (0.5%), silver nitrate (0.5%) and hypertonic saline (20%) were used as positive controls, while physiological saline was used as a negative control. After 1, 2 and 5 min, the protoscolicidal effects were determined by 1% eosin. A 25% glucose solution had no significant protoscolicidal effect. However, a 50% glucose solution revealed higher protoscolicidal effect than 0.5% silver nitrate but weaker effect than 0.5% cetrimide; the effect was comparable with that of 20% hypertonic saline. The results showed that hypertonic glucose solution is highly effective in killing protoscolices of Echinococcus granulosus in vitro.

Authors+Show Affiliations

Department of Surgery, Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. hoseiniv@sums.ac.irNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16969062

Citation

Hosseini, Seyed Vahid, et al. "In Vitro Protoscolicidal Effects of Hypertonic Glucose On Protoscolices of Hydatid Cyst." The Korean Journal of Parasitology, vol. 44, no. 3, 2006, pp. 239-42.
Hosseini SV, Ghanbarzadeh K, Barzin J, et al. In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst. Korean J Parasitol. 2006;44(3):239-42.
Hosseini, S. V., Ghanbarzadeh, K., Barzin, J., Sadjjadi, S. M., Tanideh, N., & Mehrabani, D. (2006). In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst. The Korean Journal of Parasitology, 44(3), pp. 239-42.
Hosseini SV, et al. In Vitro Protoscolicidal Effects of Hypertonic Glucose On Protoscolices of Hydatid Cyst. Korean J Parasitol. 2006;44(3):239-42. PubMed PMID: 16969062.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst. AU - Hosseini,Seyed Vahid, AU - Ghanbarzadeh,Kurosh, AU - Barzin,Jahra, AU - Sadjjadi,Seyed Mahmoud, AU - Tanideh,Nader, AU - Mehrabani,Davood, PY - 2006/9/14/pubmed PY - 2006/10/18/medline PY - 2006/9/14/entrez SP - 239 EP - 42 JF - The Korean journal of parasitology JO - Korean J. Parasitol. VL - 44 IS - 3 N2 - To evaluate the protoscolicidal effects of various concentrations of hypertonic glucose, live protoscolices of sheep were exposed to 10%, 15%, 25% and 50% glucose solutions. Cetrimide (0.5%), silver nitrate (0.5%) and hypertonic saline (20%) were used as positive controls, while physiological saline was used as a negative control. After 1, 2 and 5 min, the protoscolicidal effects were determined by 1% eosin. A 25% glucose solution had no significant protoscolicidal effect. However, a 50% glucose solution revealed higher protoscolicidal effect than 0.5% silver nitrate but weaker effect than 0.5% cetrimide; the effect was comparable with that of 20% hypertonic saline. The results showed that hypertonic glucose solution is highly effective in killing protoscolices of Echinococcus granulosus in vitro. SN - 0023-4001 UR - https://www.unboundmedicine.com/medline/citation/16969062/In_vitro_protoscolicidal_effects_of_hypertonic_glucose_on_protoscolices_of_hydatid_cyst_ L2 - http://www.parasitol.or.kr/kjp/DOIx.php?id=10.3347/kjp.2006.44.3.239 DB - PRIME DP - Unbound Medicine ER -