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Sensory sparing patterns and the sensory ratio in acute inflammatory demyelinating polyneuropathy.
Muscle Nerve. 2007 Feb; 35(2):246-50.MN

Abstract

The relative preservation (sparing) of sural sensory nerve action potentials (SNAPs) is a useful diagnostic finding in patients with acute inflammatory demyelinating polyneuropathy (AIDP). However, recording of sural SNAPs is not always technically feasible, especially in obese, edematous, or elderly individuals. Hence, we systematically evaluated the predictive values of the commonly employed SNAPs in the diagnosis of AIDP within 2 weeks from onset of symptoms. Sensory sparing patterns and sensory ratios of the sural, radial, median, and ulnar SNAPs of AIDP patients were included in a retrospective and blinded analysis, and compared to patients with diabetic polyneuropathy (DPN) and controls. Logistic regression models for the sural plus radial SNAPs/median plus ulnar SNAPs (sensory ratio) were constructed. A sural sparing pattern was present only in the AIDP group (34.4%, P < 0.001). A radial sparing pattern did not discriminate the AIDP from the DPN groups. The sural/radial sensory ratio was useful to ascertain DPN, but did not discriminate AIDP from controls. The sensory ratio was higher in AIDP compared to DPN and controls and was an independent predictor for AIDP. This study implies that the sensory ratio is a useful predictor for the diagnosis of AIDP and may substitute for sural sparing in technically difficult situations.

Authors+Show Affiliations

The Neurologic Institute, University Hospitals of Cleveland, Case School of Medicine, Cleveland, Ohio 44106-5040, USA. amer.alshekhlee@uhhs.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

16969839

Citation

Al-Shekhlee, Amer, et al. "Sensory Sparing Patterns and the Sensory Ratio in Acute Inflammatory Demyelinating Polyneuropathy." Muscle & Nerve, vol. 35, no. 2, 2007, pp. 246-50.
Al-Shekhlee A, Robinson J, Katirji B. Sensory sparing patterns and the sensory ratio in acute inflammatory demyelinating polyneuropathy. Muscle Nerve. 2007;35(2):246-50.
Al-Shekhlee, A., Robinson, J., & Katirji, B. (2007). Sensory sparing patterns and the sensory ratio in acute inflammatory demyelinating polyneuropathy. Muscle & Nerve, 35(2), 246-50.
Al-Shekhlee A, Robinson J, Katirji B. Sensory Sparing Patterns and the Sensory Ratio in Acute Inflammatory Demyelinating Polyneuropathy. Muscle Nerve. 2007;35(2):246-50. PubMed PMID: 16969839.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sensory sparing patterns and the sensory ratio in acute inflammatory demyelinating polyneuropathy. AU - Al-Shekhlee,Amer, AU - Robinson,Jenice, AU - Katirji,Bashar, PY - 2006/9/14/pubmed PY - 2007/3/28/medline PY - 2006/9/14/entrez SP - 246 EP - 50 JF - Muscle & nerve JO - Muscle Nerve VL - 35 IS - 2 N2 - The relative preservation (sparing) of sural sensory nerve action potentials (SNAPs) is a useful diagnostic finding in patients with acute inflammatory demyelinating polyneuropathy (AIDP). However, recording of sural SNAPs is not always technically feasible, especially in obese, edematous, or elderly individuals. Hence, we systematically evaluated the predictive values of the commonly employed SNAPs in the diagnosis of AIDP within 2 weeks from onset of symptoms. Sensory sparing patterns and sensory ratios of the sural, radial, median, and ulnar SNAPs of AIDP patients were included in a retrospective and blinded analysis, and compared to patients with diabetic polyneuropathy (DPN) and controls. Logistic regression models for the sural plus radial SNAPs/median plus ulnar SNAPs (sensory ratio) were constructed. A sural sparing pattern was present only in the AIDP group (34.4%, P < 0.001). A radial sparing pattern did not discriminate the AIDP from the DPN groups. The sural/radial sensory ratio was useful to ascertain DPN, but did not discriminate AIDP from controls. The sensory ratio was higher in AIDP compared to DPN and controls and was an independent predictor for AIDP. This study implies that the sensory ratio is a useful predictor for the diagnosis of AIDP and may substitute for sural sparing in technically difficult situations. SN - 0148-639X UR - https://www.unboundmedicine.com/medline/citation/16969839/Sensory_sparing_patterns_and_the_sensory_ratio_in_acute_inflammatory_demyelinating_polyneuropathy_ DB - PRIME DP - Unbound Medicine ER -