Migraine prophylaxis: who, why, and how.Cleve Clin J Med. 2006 Sep; 73(9):793-4, 797, 800-1 passim.CC
If a patient has frequent, severely debilitating migraine headaches, prophylactic treatment may help. Beta-blockers, tricyclic antidepressants, and anticonvulsants have the best evidence of efficacy; calcium channel blockers and nonsteroidal anti-inflammatory drugs are also popular because they are well tolerated and inexpensive. We review migraine treatment with emphasis on prophylaxis.