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Trends in HIV postexposure prophylaxis prescription and compliance after sexual exposure in Amsterdam, 2000-2004.
Sex Transm Dis 2007; 34(5):288-93ST

Abstract

OBJECTIVE

The objective of this study was to evaluate trends in HIV postexposure prophylaxis (PEP) requests after sexual exposure, compliance, and outcome of follow-up HIV tests.

STUDY DESIGN

The authors conducted a retrospective analysis of all HIV PEP requests after sexual exposure between January 1, 2000, and December 31, 2004, in Amsterdam.

RESULTS

In 5 years, there was a very modest increase in PEP requests, of which most (75%) came from men who have sex with men (MSM). Although 70% reported side effects, 85% completed their PEP course. Sexual assault victims less often completed their course (odds ratio [OR] = 0.1; 95% confidence interval [CI] = 0.05-0.4, P = 0.001). People who used HIV PEP more often complied with follow-up tests than people who did not use PEP (OR = 3.5; 95% CI = 1.6-7.9, P = 0.002). One HIV seroconversion was found caused by a later exposure than that for which PEP was given.

CONCLUSIONS

Despite a widely available PEP program in Amsterdam, the number of PEP requests remained low. Most people completed their PEP course; compliance with follow-up HIV testing was high.

Authors+Show Affiliations

GGD Amsterdam, Municipal Health Service Amsterdam, Department of Infectious Diseases, Amsterdam, The Netherlands. gsonder@gggd.amsterdam.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16980918

Citation

Sonder, Gerard J B., et al. "Trends in HIV Postexposure Prophylaxis Prescription and Compliance After Sexual Exposure in Amsterdam, 2000-2004." Sexually Transmitted Diseases, vol. 34, no. 5, 2007, pp. 288-93.
Sonder GJ, van den Hoek A, Regez RM, et al. Trends in HIV postexposure prophylaxis prescription and compliance after sexual exposure in Amsterdam, 2000-2004. Sex Transm Dis. 2007;34(5):288-93.
Sonder, G. J., van den Hoek, A., Regez, R. M., Brinkman, K., Prins, J. M., Mulder, J. W., ... Coutinho, R. A. (2007). Trends in HIV postexposure prophylaxis prescription and compliance after sexual exposure in Amsterdam, 2000-2004. Sexually Transmitted Diseases, 34(5), pp. 288-93.
Sonder GJ, et al. Trends in HIV Postexposure Prophylaxis Prescription and Compliance After Sexual Exposure in Amsterdam, 2000-2004. Sex Transm Dis. 2007;34(5):288-93. PubMed PMID: 16980918.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Trends in HIV postexposure prophylaxis prescription and compliance after sexual exposure in Amsterdam, 2000-2004. AU - Sonder,Gerard J B, AU - van den Hoek,Anneke, AU - Regez,Rosa M, AU - Brinkman,Kees, AU - Prins,Jan M, AU - Mulder,Jan-Willem, AU - Veenstra,Jan, AU - Claessen,Frans A, AU - Coutinho,Roel A, PY - 2006/9/19/pubmed PY - 2007/6/15/medline PY - 2006/9/19/entrez SP - 288 EP - 93 JF - Sexually transmitted diseases JO - Sex Transm Dis VL - 34 IS - 5 N2 - OBJECTIVE: The objective of this study was to evaluate trends in HIV postexposure prophylaxis (PEP) requests after sexual exposure, compliance, and outcome of follow-up HIV tests. STUDY DESIGN: The authors conducted a retrospective analysis of all HIV PEP requests after sexual exposure between January 1, 2000, and December 31, 2004, in Amsterdam. RESULTS: In 5 years, there was a very modest increase in PEP requests, of which most (75%) came from men who have sex with men (MSM). Although 70% reported side effects, 85% completed their PEP course. Sexual assault victims less often completed their course (odds ratio [OR] = 0.1; 95% confidence interval [CI] = 0.05-0.4, P = 0.001). People who used HIV PEP more often complied with follow-up tests than people who did not use PEP (OR = 3.5; 95% CI = 1.6-7.9, P = 0.002). One HIV seroconversion was found caused by a later exposure than that for which PEP was given. CONCLUSIONS: Despite a widely available PEP program in Amsterdam, the number of PEP requests remained low. Most people completed their PEP course; compliance with follow-up HIV testing was high. SN - 0148-5717 UR - https://www.unboundmedicine.com/medline/citation/16980918/Trends_in_HIV_postexposure_prophylaxis_prescription_and_compliance_after_sexual_exposure_in_Amsterdam_2000_2004_ L2 - http://Insights.ovid.com/pubmed?pmid=16980918 DB - PRIME DP - Unbound Medicine ER -