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Visual function in human ocular toxoplasmosis.
Br J Ophthalmol 2007; 91(2):233-6BJ

Abstract

AIM

To assess functional impairment in terms of visual acuity reduction and visual field defects in inactive ocular toxoplasmosis.

METHODS

61 patients with known ocular toxoplasmosis in a quiescent state were included in this prospective, cross-sectional study. A complete ophthalmic examination, retinal photodocumentation and standard automated perimetry (Octopus perimeter, program G2) were performed. Visual acuity was classified on the basis of the World Health Organization definition of visual impairment and blindness: normal (> or =20/25), mild (20/25 to 20/60), moderate (20/60 to 20/400) and severe (<20/400). Visual field damage was correspondingly graded as mild (mean defect <4 dB), moderate (mean defect 4-12 dB) or severe (mean defect >12 dB).

RESULTS

8 (13%) patients presented with bilateral ocular toxoplasmosis. Thus, a total of 69 eyes was evaluated. Visual field damage was encountered in 65 (94%) eyes, whereas only 28 (41%) eyes had reduced visual acuity, showing perimetric findings to be more sensitive in detecting chorioretinal damage (p<0.001). Correlation with the clinical localisation of chorioretinal scars was better for visual field (in 70% of the instances) than for visual acuity (33%). Moderate to severe functional impairment was registered in 65.2% for visual field, and in 27.5% for visual acuity.

CONCLUSION

In its quiescent stage, ocular toxoplasmosis was associated with permanent visual field defects in >94% of the eyes studied. Hence, standard automated perimetry may better reflect the functional damage encountered by ocular toxoplasmosis than visual acuity.

Authors+Show Affiliations

Department of Ophthalmology, University of Bern, Bern, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16987904

Citation

Scherrer, Janine, et al. "Visual Function in Human Ocular Toxoplasmosis." The British Journal of Ophthalmology, vol. 91, no. 2, 2007, pp. 233-6.
Scherrer J, Iliev ME, Halberstadt M, et al. Visual function in human ocular toxoplasmosis. Br J Ophthalmol. 2007;91(2):233-6.
Scherrer, J., Iliev, M. E., Halberstadt, M., Kodjikian, L., & Garweg, J. G. (2007). Visual function in human ocular toxoplasmosis. The British Journal of Ophthalmology, 91(2), pp. 233-6.
Scherrer J, et al. Visual Function in Human Ocular Toxoplasmosis. Br J Ophthalmol. 2007;91(2):233-6. PubMed PMID: 16987904.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Visual function in human ocular toxoplasmosis. AU - Scherrer,Janine, AU - Iliev,Milko E, AU - Halberstadt,Markus, AU - Kodjikian,Laurent, AU - Garweg,Justus G, Y1 - 2006/09/20/ PY - 2006/9/22/pubmed PY - 2007/2/21/medline PY - 2006/9/22/entrez SP - 233 EP - 6 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 91 IS - 2 N2 - AIM: To assess functional impairment in terms of visual acuity reduction and visual field defects in inactive ocular toxoplasmosis. METHODS: 61 patients with known ocular toxoplasmosis in a quiescent state were included in this prospective, cross-sectional study. A complete ophthalmic examination, retinal photodocumentation and standard automated perimetry (Octopus perimeter, program G2) were performed. Visual acuity was classified on the basis of the World Health Organization definition of visual impairment and blindness: normal (> or =20/25), mild (20/25 to 20/60), moderate (20/60 to 20/400) and severe (<20/400). Visual field damage was correspondingly graded as mild (mean defect <4 dB), moderate (mean defect 4-12 dB) or severe (mean defect >12 dB). RESULTS: 8 (13%) patients presented with bilateral ocular toxoplasmosis. Thus, a total of 69 eyes was evaluated. Visual field damage was encountered in 65 (94%) eyes, whereas only 28 (41%) eyes had reduced visual acuity, showing perimetric findings to be more sensitive in detecting chorioretinal damage (p<0.001). Correlation with the clinical localisation of chorioretinal scars was better for visual field (in 70% of the instances) than for visual acuity (33%). Moderate to severe functional impairment was registered in 65.2% for visual field, and in 27.5% for visual acuity. CONCLUSION: In its quiescent stage, ocular toxoplasmosis was associated with permanent visual field defects in >94% of the eyes studied. Hence, standard automated perimetry may better reflect the functional damage encountered by ocular toxoplasmosis than visual acuity. SN - 0007-1161 UR - https://www.unboundmedicine.com/medline/citation/16987904/Visual_function_in_human_ocular_toxoplasmosis_ L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=16987904 DB - PRIME DP - Unbound Medicine ER -