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Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus.
Diabetes Care 2006; 29(10):2223-30DC

Abstract

OBJECTIVE

We aimed to examine whether pregravid dietary fiber consumptions from cereal, fruit, and vegetable sources and dietary glycemic load were related to gestational diabetes mellitus (GDM) risk.

RESEARCH DESIGN AND METHODS

This study was a prospective cohort study among 13,110 eligible women in the Nurses' Health Study II. GDM was self-reported and validated by medical record review in a subsample.

RESULTS

We documented 758 incident GDM cases during 8 years of follow-up. After adjustment for age, parity, prepregnancy BMI, and other covariates, dietary total fiber and cereal and fruit fiber were strongly associated with GDM risk. Each 10-g/day increment in total fiber intake was associated with 26% (95% CI 9-49) reduction in risk; each 5-g/day increment in cereal or fruit fiber was associated with a 23% (9-36) or 26% (5-42) reduction, respectively. Dietary glycemic load was positively related to GDM risk. Multivariate relative risk for highest versus lowest quintiles was 1.61 (1.02-2.53) (P for trend 0.03). The combination of high-glycemic load and low-cereal fiber diet was associated with 2.15-fold (1.04-4.29) increased risk compared with the reciprocal diet.

CONCLUSIONS

These findings suggested that prepregnancy diet might be associated with women's GDM risk. In particular, diet with low fiber and high glycemic load was associated with an increased risk. Future clinical and metabolic studies are warranted to confirm these findings.

Authors+Show Affiliations

Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115, USA. cuilin.zhang@channing.harvard.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

17003297

Citation

Zhang, Cuilin, et al. "Dietary Fiber Intake, Dietary Glycemic Load, and the Risk for Gestational Diabetes Mellitus." Diabetes Care, vol. 29, no. 10, 2006, pp. 2223-30.
Zhang C, Liu S, Solomon CG, et al. Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus. Diabetes Care. 2006;29(10):2223-30.
Zhang, C., Liu, S., Solomon, C. G., & Hu, F. B. (2006). Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus. Diabetes Care, 29(10), pp. 2223-30.
Zhang C, et al. Dietary Fiber Intake, Dietary Glycemic Load, and the Risk for Gestational Diabetes Mellitus. Diabetes Care. 2006;29(10):2223-30. PubMed PMID: 17003297.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus. AU - Zhang,Cuilin, AU - Liu,Simin, AU - Solomon,Caren G, AU - Hu,Frank B, PY - 2006/9/28/pubmed PY - 2007/1/6/medline PY - 2006/9/28/entrez SP - 2223 EP - 30 JF - Diabetes care JO - Diabetes Care VL - 29 IS - 10 N2 - OBJECTIVE: We aimed to examine whether pregravid dietary fiber consumptions from cereal, fruit, and vegetable sources and dietary glycemic load were related to gestational diabetes mellitus (GDM) risk. RESEARCH DESIGN AND METHODS: This study was a prospective cohort study among 13,110 eligible women in the Nurses' Health Study II. GDM was self-reported and validated by medical record review in a subsample. RESULTS: We documented 758 incident GDM cases during 8 years of follow-up. After adjustment for age, parity, prepregnancy BMI, and other covariates, dietary total fiber and cereal and fruit fiber were strongly associated with GDM risk. Each 10-g/day increment in total fiber intake was associated with 26% (95% CI 9-49) reduction in risk; each 5-g/day increment in cereal or fruit fiber was associated with a 23% (9-36) or 26% (5-42) reduction, respectively. Dietary glycemic load was positively related to GDM risk. Multivariate relative risk for highest versus lowest quintiles was 1.61 (1.02-2.53) (P for trend 0.03). The combination of high-glycemic load and low-cereal fiber diet was associated with 2.15-fold (1.04-4.29) increased risk compared with the reciprocal diet. CONCLUSIONS: These findings suggested that prepregnancy diet might be associated with women's GDM risk. In particular, diet with low fiber and high glycemic load was associated with an increased risk. Future clinical and metabolic studies are warranted to confirm these findings. SN - 0149-5992 UR - https://www.unboundmedicine.com/medline/citation/17003297/full_citation L2 - http://care.diabetesjournals.org/cgi/pmidlookup?view=long&pmid=17003297 DB - PRIME DP - Unbound Medicine ER -