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Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus.

Abstract

OBJECTIVE

We aimed to examine whether pregravid dietary fiber consumptions from cereal, fruit, and vegetable sources and dietary glycemic load were related to gestational diabetes mellitus (GDM) risk.

RESEARCH DESIGN AND METHODS

This study was a prospective cohort study among 13,110 eligible women in the Nurses' Health Study II. GDM was self-reported and validated by medical record review in a subsample.

RESULTS

We documented 758 incident GDM cases during 8 years of follow-up. After adjustment for age, parity, prepregnancy BMI, and other covariates, dietary total fiber and cereal and fruit fiber were strongly associated with GDM risk. Each 10-g/day increment in total fiber intake was associated with 26% (95% CI 9-49) reduction in risk; each 5-g/day increment in cereal or fruit fiber was associated with a 23% (9-36) or 26% (5-42) reduction, respectively. Dietary glycemic load was positively related to GDM risk. Multivariate relative risk for highest versus lowest quintiles was 1.61 (1.02-2.53) (P for trend 0.03). The combination of high-glycemic load and low-cereal fiber diet was associated with 2.15-fold (1.04-4.29) increased risk compared with the reciprocal diet.

CONCLUSIONS

These findings suggested that prepregnancy diet might be associated with women's GDM risk. In particular, diet with low fiber and high glycemic load was associated with an increased risk. Future clinical and metabolic studies are warranted to confirm these findings.

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  • Authors+Show Affiliations

    ,

    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115, USA. cuilin.zhang@channing.harvard.edu

    , ,

    Source

    Diabetes care 29:10 2006 Oct pg 2223-30

    MeSH

    Adult
    Cohort Studies
    Diabetes, Gestational
    Dietary Fiber
    Edible Grain
    Female
    Fruit
    Glycemic Index
    Humans
    Magnesium
    Pregnancy
    Prospective Studies
    Risk
    Vegetables

    Pub Type(s)

    Journal Article
    Research Support, N.I.H., Extramural

    Language

    eng

    PubMed ID

    17003297

    Citation

    Zhang, Cuilin, et al. "Dietary Fiber Intake, Dietary Glycemic Load, and the Risk for Gestational Diabetes Mellitus." Diabetes Care, vol. 29, no. 10, 2006, pp. 2223-30.
    Zhang C, Liu S, Solomon CG, et al. Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus. Diabetes Care. 2006;29(10):2223-30.
    Zhang, C., Liu, S., Solomon, C. G., & Hu, F. B. (2006). Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus. Diabetes Care, 29(10), pp. 2223-30.
    Zhang C, et al. Dietary Fiber Intake, Dietary Glycemic Load, and the Risk for Gestational Diabetes Mellitus. Diabetes Care. 2006;29(10):2223-30. PubMed PMID: 17003297.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus. AU - Zhang,Cuilin, AU - Liu,Simin, AU - Solomon,Caren G, AU - Hu,Frank B, PY - 2006/9/28/pubmed PY - 2007/1/6/medline PY - 2006/9/28/entrez SP - 2223 EP - 30 JF - Diabetes care JO - Diabetes Care VL - 29 IS - 10 N2 - OBJECTIVE: We aimed to examine whether pregravid dietary fiber consumptions from cereal, fruit, and vegetable sources and dietary glycemic load were related to gestational diabetes mellitus (GDM) risk. RESEARCH DESIGN AND METHODS: This study was a prospective cohort study among 13,110 eligible women in the Nurses' Health Study II. GDM was self-reported and validated by medical record review in a subsample. RESULTS: We documented 758 incident GDM cases during 8 years of follow-up. After adjustment for age, parity, prepregnancy BMI, and other covariates, dietary total fiber and cereal and fruit fiber were strongly associated with GDM risk. Each 10-g/day increment in total fiber intake was associated with 26% (95% CI 9-49) reduction in risk; each 5-g/day increment in cereal or fruit fiber was associated with a 23% (9-36) or 26% (5-42) reduction, respectively. Dietary glycemic load was positively related to GDM risk. Multivariate relative risk for highest versus lowest quintiles was 1.61 (1.02-2.53) (P for trend 0.03). The combination of high-glycemic load and low-cereal fiber diet was associated with 2.15-fold (1.04-4.29) increased risk compared with the reciprocal diet. CONCLUSIONS: These findings suggested that prepregnancy diet might be associated with women's GDM risk. In particular, diet with low fiber and high glycemic load was associated with an increased risk. Future clinical and metabolic studies are warranted to confirm these findings. SN - 0149-5992 UR - https://www.unboundmedicine.com/medline/citation/17003297/full_citation L2 - http://care.diabetesjournals.org/cgi/pmidlookup?view=long&pmid=17003297 DB - PRIME DP - Unbound Medicine ER -