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Evaluation on scolicidal efficacy of propolis.
Eur Surg Res 2006; 38(5):476-81ES

Abstract

BACKGROUND

Propolis is a resinous material collected by bees from various plants. It has antimicrobial, antioxidative, immunostimulative, and regenerative properties. We determined the scolicidal effect of propolis in different concentrations and various exposure times.

MATERIALS AND METHODS

Tubes containing Echinococcus granulosus protoscoleces were supplemented with different concentrations of ethyl alcohol extract of propolis. At the end of the incubation times, viability of protoscoleces was assessed by trypan blue exclusion test. We also applied 5 ml of 1 microg/ml propolis intraperitoneally for determination of side effects and mortality rates.

RESULTS

We determined that 1 microg/ml concentration of propolis killed all of the protoscoleces at the end of the 3rd minute. In the in vivo part of the study, intraperitoneal application of propolis did not cause any side effects or mortality.

CONCLUSION

We concluded that this natural agent can be used as a potent scolicidal agent after studies which will determine in vivo efficacy and the effects on liver and biliary tree when injected directly into the common bile duct.

Authors+Show Affiliations

Department of General Surgery, Ankara Training and Research Hospital, Ankara, Turkey. kemalkismet@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17008792

Citation

Kismet, Kemal, et al. "Evaluation On Scolicidal Efficacy of Propolis." European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes, vol. 38, no. 5, 2006, pp. 476-81.
Kismet K, Kilicoglu B, Koru O, et al. Evaluation on scolicidal efficacy of propolis. Eur Surg Res. 2006;38(5):476-81.
Kismet, K., Kilicoglu, B., Koru, O., Tanyuksel, M., Oruc, M. T., Sorkun, K., ... Akkus, M. A. (2006). Evaluation on scolicidal efficacy of propolis. European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes, 38(5), pp. 476-81.
Kismet K, et al. Evaluation On Scolicidal Efficacy of Propolis. Eur Surg Res. 2006;38(5):476-81. PubMed PMID: 17008792.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation on scolicidal efficacy of propolis. AU - Kismet,Kemal, AU - Kilicoglu,Bulent, AU - Koru,Ozgur, AU - Tanyuksel,Mehmet, AU - Oruc,Mehmet Tahir, AU - Sorkun,Kadriye, AU - Salih,Bekir, AU - Akkus,Mehmet Ali, Y1 - 2006/09/29/ PY - 2006/04/22/received PY - 2006/07/25/accepted PY - 2006/9/30/pubmed PY - 2006/12/9/medline PY - 2006/9/30/entrez SP - 476 EP - 81 JF - European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes JO - Eur Surg Res VL - 38 IS - 5 N2 - BACKGROUND: Propolis is a resinous material collected by bees from various plants. It has antimicrobial, antioxidative, immunostimulative, and regenerative properties. We determined the scolicidal effect of propolis in different concentrations and various exposure times. MATERIALS AND METHODS: Tubes containing Echinococcus granulosus protoscoleces were supplemented with different concentrations of ethyl alcohol extract of propolis. At the end of the incubation times, viability of protoscoleces was assessed by trypan blue exclusion test. We also applied 5 ml of 1 microg/ml propolis intraperitoneally for determination of side effects and mortality rates. RESULTS: We determined that 1 microg/ml concentration of propolis killed all of the protoscoleces at the end of the 3rd minute. In the in vivo part of the study, intraperitoneal application of propolis did not cause any side effects or mortality. CONCLUSION: We concluded that this natural agent can be used as a potent scolicidal agent after studies which will determine in vivo efficacy and the effects on liver and biliary tree when injected directly into the common bile duct. SN - 0014-312X UR - https://www.unboundmedicine.com/medline/citation/17008792/Evaluation_on_scolicidal_efficacy_of_propolis_ L2 - https://www.karger.com?DOI=10.1159/000096006 DB - PRIME DP - Unbound Medicine ER -