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Retinal vascular abnormalities and prevalence of age-related macular degeneration in adult Chinese: the Beijing Eye Study.
Am J Ophthalmol 2006; 142(4):688-9AJ

Abstract

PURPOSE

To evaluate whether retinal vessel abnormalities are associated with early or late age-related macular degeneration (AMD) in adult Chinese.

DESIGN

Population-based prevalence study.

METHODS

The Beijing Eye Study included 4439 (83.4%) subjects of 5324 living in a rural area or urban region of Greater Beijing, age older than 40+ years, and invited to participate. The participants underwent a detailed ophthalmic examination, including fundus photography. The photographs were graded using the Wisconsin Age-Related Maculopathy Grading system for evaluation of AMD, and using the Atherosclerosis Risk in Communities protocol for assessment of retinal vascular abnormalities. We examined focal and generalized arteriolar narrowing, arteriolar sheathing, and arteriovenous crossing abnormalities.

RESULTS

Fundus photographs were available for 8655 eyes of 4376 (98.6%) subjects. Neither early nor late AMD was significantly (P > .15) associated with any of the retinal vascular abnormalities.

CONCLUSIONS

Retinal vascular abnormalities are not markedly associated with the prevalence of early or late AMD.

Authors+Show Affiliations

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center and Capital University of Medical Science, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17011870

Citation

Xu, Liang, et al. "Retinal Vascular Abnormalities and Prevalence of Age-related Macular Degeneration in Adult Chinese: the Beijing Eye Study." American Journal of Ophthalmology, vol. 142, no. 4, 2006, pp. 688-9.
Xu L, Wang S, Li Y, et al. Retinal vascular abnormalities and prevalence of age-related macular degeneration in adult Chinese: the Beijing Eye Study. Am J Ophthalmol. 2006;142(4):688-9.
Xu, L., Wang, S., Li, Y., & Jonas, J. B. (2006). Retinal vascular abnormalities and prevalence of age-related macular degeneration in adult Chinese: the Beijing Eye Study. American Journal of Ophthalmology, 142(4), pp. 688-9.
Xu L, et al. Retinal Vascular Abnormalities and Prevalence of Age-related Macular Degeneration in Adult Chinese: the Beijing Eye Study. Am J Ophthalmol. 2006;142(4):688-9. PubMed PMID: 17011870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Retinal vascular abnormalities and prevalence of age-related macular degeneration in adult Chinese: the Beijing Eye Study. AU - Xu,Liang, AU - Wang,Shuang, AU - Li,Yibin, AU - Jonas,Jost B, PY - 2006/02/15/received PY - 2006/05/09/revised PY - 2006/05/10/accepted PY - 2006/10/3/pubmed PY - 2006/10/27/medline PY - 2006/10/3/entrez SP - 688 EP - 9 JF - American journal of ophthalmology JO - Am. J. Ophthalmol. VL - 142 IS - 4 N2 - PURPOSE: To evaluate whether retinal vessel abnormalities are associated with early or late age-related macular degeneration (AMD) in adult Chinese. DESIGN: Population-based prevalence study. METHODS: The Beijing Eye Study included 4439 (83.4%) subjects of 5324 living in a rural area or urban region of Greater Beijing, age older than 40+ years, and invited to participate. The participants underwent a detailed ophthalmic examination, including fundus photography. The photographs were graded using the Wisconsin Age-Related Maculopathy Grading system for evaluation of AMD, and using the Atherosclerosis Risk in Communities protocol for assessment of retinal vascular abnormalities. We examined focal and generalized arteriolar narrowing, arteriolar sheathing, and arteriovenous crossing abnormalities. RESULTS: Fundus photographs were available for 8655 eyes of 4376 (98.6%) subjects. Neither early nor late AMD was significantly (P > .15) associated with any of the retinal vascular abnormalities. CONCLUSIONS: Retinal vascular abnormalities are not markedly associated with the prevalence of early or late AMD. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/17011870/Retinal_vascular_abnormalities_and_prevalence_of_age_related_macular_degeneration_in_adult_Chinese:_the_Beijing_Eye_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(06)00608-8 DB - PRIME DP - Unbound Medicine ER -