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Synthesis of a molecularly imprinted polymer for the selective solid-phase extraction of chloramphenicol from honey.
J Chromatogr A. 2006 Nov 03; 1132(1-2):325-8.JC

Abstract

Solid-phase extraction (SPE) with a molecularly imprinted polymer (MIP) as sorbent has been investigated for the clean-up of the broad-spectrum bacteriostatic antibiotic chloramphenicol (CAP) in honey samples. The MIP was prepared by using methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EDMA) as cross-linker, chloroform as porogen and CAP as template molecule. The binding behaviour of the template CAP on the MIP was evaluated by high-performance liquid chromatography, and then the MIP was applied as a sorbent in SPE to selectively extract CAP from honey. It was shown that recoveries of nearly 100% of a CAP standard solution and up to 94% from spiked honey samples could be obtained after SPE.

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Authors+Show Affiliations

Schirmer C
Institute of Dairy Chemistry and Technology, Federal Research Centre for Nutrition and Food (BfEL) Location Kiel, Hermann-Weigmann-Strasse 1, D-24103 Kiel, Germany.
Meisel H
No affiliation info available

MeSH

ChloramphenicolChromatography, LiquidHoneyMethacrylatesPolymersReproducibility of ResultsSolvents

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17014862

Citation

Schirmer, Christina, and Hans Meisel. "Synthesis of a Molecularly Imprinted Polymer for the Selective Solid-phase Extraction of Chloramphenicol From Honey." Journal of Chromatography. A, vol. 1132, no. 1-2, 2006, pp. 325-8.
Schirmer C, Meisel H. Synthesis of a molecularly imprinted polymer for the selective solid-phase extraction of chloramphenicol from honey. J Chromatogr A. 2006;1132(1-2):325-8.
Schirmer, C., & Meisel, H. (2006). Synthesis of a molecularly imprinted polymer for the selective solid-phase extraction of chloramphenicol from honey. Journal of Chromatography. A, 1132(1-2), 325-8.
Schirmer C, Meisel H. Synthesis of a Molecularly Imprinted Polymer for the Selective Solid-phase Extraction of Chloramphenicol From Honey. J Chromatogr A. 2006 Nov 3;1132(1-2):325-8. PubMed PMID: 17014862.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of a molecularly imprinted polymer for the selective solid-phase extraction of chloramphenicol from honey. AU - Schirmer,Christina, AU - Meisel,Hans, Y1 - 2006/10/02/ PY - 2006/07/03/received PY - 2006/09/08/revised PY - 2006/09/14/accepted PY - 2006/10/4/pubmed PY - 2006/12/16/medline PY - 2006/10/4/entrez SP - 325 EP - 8 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1132 IS - 1-2 N2 - Solid-phase extraction (SPE) with a molecularly imprinted polymer (MIP) as sorbent has been investigated for the clean-up of the broad-spectrum bacteriostatic antibiotic chloramphenicol (CAP) in honey samples. The MIP was prepared by using methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EDMA) as cross-linker, chloroform as porogen and CAP as template molecule. The binding behaviour of the template CAP on the MIP was evaluated by high-performance liquid chromatography, and then the MIP was applied as a sorbent in SPE to selectively extract CAP from honey. It was shown that recoveries of nearly 100% of a CAP standard solution and up to 94% from spiked honey samples could be obtained after SPE. SN - 0021-9673 UR - https://www.unboundmedicine.com/medline/citation/17014862/Synthesis_of_a_molecularly_imprinted_polymer_for_the_selective_solid_phase_extraction_of_chloramphenicol_from_honey_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9673(06)01781-X DB - PRIME DP - Unbound Medicine ER -