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[Is hyperuricemia a cardiovascular risk factor?].
Wiad Lek. 2006; 59(5-6):364-7.WL

Abstract

The association of elevated serum uric acid (hyperuricemia, gout) with the presence of classical coronary risk factors and coronary artery disease (CAD) or myocardial infarction (MI) has been analysed in many epidemiological studies. Numerous studies have revealed that hypertension, high body mass index (BMI), lipid disorders (especially raised triglycerides--TG level and low high dense lipoprotein cholesterol HDL-C level), increased creatinine or insulin levels have caused hyperuricemia. No association has been observed between hyperuricemia and diabetes type 2 and uricemia and glicemia. But in some studies the relationship between cholesterol and uric acid levels has been not confirmed. Hyperuricemia has been observed in patients with non-treated hypertension. Gout has often occurred with typical disorders for the metabolic syndrome X. Significant correlation of the serum uric level and the CAD presence and severity of coronary atherosclerosis confirmed by coronary angiography has been observed in women. Hyperuricemia has also indirect influence on progress of CAD by physical activity restriction, what causes sedentary mode of life and lead to obesity. Obesity is a known risk factor diabetes, lipid disorders and hypertension. To recapitulate, it is a matter of controversy as to whether uric acid is an independent cardiovascular risk factor or rather it only represents reinforcement of typical risk factor.

Authors+Show Affiliations

Zakładu Kardiologii Inwazyjnej Uniwersytetu Medycznego w Lodzi.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

pol

PubMed ID

17017483

Citation

Chizyński, Krzysztof, and Monika Rózycka. "[Is Hyperuricemia a Cardiovascular Risk Factor?]." Wiadomosci Lekarskie (Warsaw, Poland : 1960), vol. 59, no. 5-6, 2006, pp. 364-7.
Chizyński K, Rózycka M. [Is hyperuricemia a cardiovascular risk factor?]. Wiad Lek. 2006;59(5-6):364-7.
Chizyński, K., & Rózycka, M. (2006). [Is hyperuricemia a cardiovascular risk factor?]. Wiadomosci Lekarskie (Warsaw, Poland : 1960), 59(5-6), 364-7.
Chizyński K, Rózycka M. [Is Hyperuricemia a Cardiovascular Risk Factor?]. Wiad Lek. 2006;59(5-6):364-7. PubMed PMID: 17017483.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Is hyperuricemia a cardiovascular risk factor?]. AU - Chizyński,Krzysztof, AU - Rózycka,Monika, PY - 2006/10/5/pubmed PY - 2006/12/15/medline PY - 2006/10/5/entrez SP - 364 EP - 7 JF - Wiadomosci lekarskie (Warsaw, Poland : 1960) JO - Wiad Lek VL - 59 IS - 5-6 N2 - The association of elevated serum uric acid (hyperuricemia, gout) with the presence of classical coronary risk factors and coronary artery disease (CAD) or myocardial infarction (MI) has been analysed in many epidemiological studies. Numerous studies have revealed that hypertension, high body mass index (BMI), lipid disorders (especially raised triglycerides--TG level and low high dense lipoprotein cholesterol HDL-C level), increased creatinine or insulin levels have caused hyperuricemia. No association has been observed between hyperuricemia and diabetes type 2 and uricemia and glicemia. But in some studies the relationship between cholesterol and uric acid levels has been not confirmed. Hyperuricemia has been observed in patients with non-treated hypertension. Gout has often occurred with typical disorders for the metabolic syndrome X. Significant correlation of the serum uric level and the CAD presence and severity of coronary atherosclerosis confirmed by coronary angiography has been observed in women. Hyperuricemia has also indirect influence on progress of CAD by physical activity restriction, what causes sedentary mode of life and lead to obesity. Obesity is a known risk factor diabetes, lipid disorders and hypertension. To recapitulate, it is a matter of controversy as to whether uric acid is an independent cardiovascular risk factor or rather it only represents reinforcement of typical risk factor. SN - 0043-5147 UR - https://www.unboundmedicine.com/medline/citation/17017483/[Is_hyperuricemia_a_cardiovascular_risk_factor]_ DB - PRIME DP - Unbound Medicine ER -
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