Palladium-catalyzed selective 2,3-diarylation of alpha,alpha-disubstituted 3-thiophenemethanols via cleavage of C-H and C-C bonds.J Org Chem. 2006 Oct 13; 71(21):8309-11.JO
Abstract
Alpha,alpha-disubstituted 3-thiophenemethanols undergo selective diarylation accompanied by cleavage of the C-H and C-C bonds of the 2- and 3-positions, respectively, upon treatment with aryl bromides in the presence of a palladium catalyst to give the corresponding 2,3-diarylthiophenes in good yields.
Pub Type(s)
Journal Article
Language
eng
PubMed ID
17025334
Citation
Nakano, Masaya, et al. "Palladium-catalyzed Selective 2,3-diarylation of Alpha,alpha-disubstituted 3-thiophenemethanols Via Cleavage of C-H and C-C Bonds." The Journal of Organic Chemistry, vol. 71, no. 21, 2006, pp. 8309-11.
Nakano M, Satoh T, Miura M. Palladium-catalyzed selective 2,3-diarylation of alpha,alpha-disubstituted 3-thiophenemethanols via cleavage of C-H and C-C bonds. J Org Chem. 2006;71(21):8309-11.
Nakano, M., Satoh, T., & Miura, M. (2006). Palladium-catalyzed selective 2,3-diarylation of alpha,alpha-disubstituted 3-thiophenemethanols via cleavage of C-H and C-C bonds. The Journal of Organic Chemistry, 71(21), 8309-11.
Nakano M, Satoh T, Miura M. Palladium-catalyzed Selective 2,3-diarylation of Alpha,alpha-disubstituted 3-thiophenemethanols Via Cleavage of C-H and C-C Bonds. J Org Chem. 2006 Oct 13;71(21):8309-11. PubMed PMID: 17025334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Palladium-catalyzed selective 2,3-diarylation of alpha,alpha-disubstituted 3-thiophenemethanols via cleavage of C-H and C-C bonds.
AU - Nakano,Masaya,
AU - Satoh,Tetsuya,
AU - Miura,Masahiro,
PY - 2006/10/10/pubmed
PY - 2006/10/10/medline
PY - 2006/10/10/entrez
SP - 8309
EP - 11
JF - The Journal of organic chemistry
JO - J Org Chem
VL - 71
IS - 21
N2 - Alpha,alpha-disubstituted 3-thiophenemethanols undergo selective diarylation accompanied by cleavage of the C-H and C-C bonds of the 2- and 3-positions, respectively, upon treatment with aryl bromides in the presence of a palladium catalyst to give the corresponding 2,3-diarylthiophenes in good yields.
SN - 0022-3263
UR - https://www.unboundmedicine.com/medline/citation/17025334/Palladium_catalyzed_selective_23_diarylation_of_alphaalpha_disubstituted_3_thiophenemethanols_via_cleavage_of_C_H_and_C_C_bonds_
L2 - https://doi.org/10.1021/jo061412e
DB - PRIME
DP - Unbound Medicine
ER -
