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Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques.
Skin Res Technol. 2006 Nov; 12(4):241-6.SR

Abstract

BACKGROUND/PURPOSE

The polysaccharide-rich composition of Aloe vera extracts (Aloe barbadensis Miller), often used in cosmetic formulations, may impart moisturizing properties to the product. The aim of this study was to evaluate the effect of cosmetic formulations containing different concentrations of freeze-dried Aloe vera extract on skin hydration, after a single and a 1- and 2-week period of application, by using skin bioengineering techniques.

METHODS

Stable formulations containing 5% (w/w) of a trilaureth-4 phosphate-based blend were supplemented with 0.10%, 0.25% or 0.50% (w/w) of freeze-dried Aloe vera extract and applied to the volar forearm of 20 female subjects. Skin conditions in terms of the water content of the stratum corneum and of transepidermal water loss (TEWL) (Corneometer CM 825 and Tewameter TM 210) were analysed before and after a single and 1- and 2-week period of daily application.

RESULTS

After a single application, only formulations supplemented with 0.25% and 0.50% (w/w) of Aloe vera extract increased the water content of the stratum corneum, while after the 2-week period application, all formulations containing the extract (0.10%, 0.25% and 0.50%) had the same effect, in both cases as compared with the vehicle. TEWL was not modified after a single and after 1- and 2-week period of application, when compared with the vehicle.

CONCLUSION

Our results show that freeze-dried Aloe vera extract is a natural effective ingredient for improving skin hydration, possibly through a humectant mechanism. Consequently, it may be used in moisturizing cosmetic formulations and also as a complement in the treatment of dry skin.

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Authors+Show Affiliations

Dal'Belo SE
Laboratory of Cosmetic Technology, Faculdade de Ciencias Farmaceuticas de Ribeirão Preto, University of São Paulo, Brazil.
Gaspar LR
No affiliation info available
Maia Campos PM
No affiliation info available

MeSH

AdultAloeBiomedical EngineeringBody WaterCosmeticsDrug Administration ScheduleEpidermisFemaleFreeze DryingHumansOsmolar ConcentrationPlant ExtractsSkinWater Loss, Insensible

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17026654

Citation

Dal'Belo, Susi Elaine, et al. "Moisturizing Effect of Cosmetic Formulations Containing Aloe Vera Extract in Different Concentrations Assessed By Skin Bioengineering Techniques." Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), vol. 12, no. 4, 2006, pp. 241-6.
Dal'Belo SE, Gaspar LR, Maia Campos PM. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res Technol. 2006;12(4):241-6.
Dal'Belo, S. E., Gaspar, L. R., & Maia Campos, P. M. (2006). Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 12(4), 241-6.
Dal'Belo SE, Gaspar LR, Maia Campos PM. Moisturizing Effect of Cosmetic Formulations Containing Aloe Vera Extract in Different Concentrations Assessed By Skin Bioengineering Techniques. Skin Res Technol. 2006;12(4):241-6. PubMed PMID: 17026654.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. AU - Dal'Belo,Susi Elaine, AU - Gaspar,Lorena Rigo, AU - Maia Campos,Patrícia Maria Berardo Gonçalves, PY - 2006/10/10/pubmed PY - 2007/1/11/medline PY - 2006/10/10/entrez SP - 241 EP - 6 JF - Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) JO - Skin Res Technol VL - 12 IS - 4 N2 - BACKGROUND/PURPOSE: The polysaccharide-rich composition of Aloe vera extracts (Aloe barbadensis Miller), often used in cosmetic formulations, may impart moisturizing properties to the product. The aim of this study was to evaluate the effect of cosmetic formulations containing different concentrations of freeze-dried Aloe vera extract on skin hydration, after a single and a 1- and 2-week period of application, by using skin bioengineering techniques. METHODS: Stable formulations containing 5% (w/w) of a trilaureth-4 phosphate-based blend were supplemented with 0.10%, 0.25% or 0.50% (w/w) of freeze-dried Aloe vera extract and applied to the volar forearm of 20 female subjects. Skin conditions in terms of the water content of the stratum corneum and of transepidermal water loss (TEWL) (Corneometer CM 825 and Tewameter TM 210) were analysed before and after a single and 1- and 2-week period of daily application. RESULTS: After a single application, only formulations supplemented with 0.25% and 0.50% (w/w) of Aloe vera extract increased the water content of the stratum corneum, while after the 2-week period application, all formulations containing the extract (0.10%, 0.25% and 0.50%) had the same effect, in both cases as compared with the vehicle. TEWL was not modified after a single and after 1- and 2-week period of application, when compared with the vehicle. CONCLUSION: Our results show that freeze-dried Aloe vera extract is a natural effective ingredient for improving skin hydration, possibly through a humectant mechanism. Consequently, it may be used in moisturizing cosmetic formulations and also as a complement in the treatment of dry skin. SN - 0909-752X UR - https://www.unboundmedicine.com/medline/citation/17026654/Moisturizing_effect_of_cosmetic_formulations_containing_Aloe_vera_extract_in_different_concentrations_assessed_by_skin_bioengineering_techniques_ L2 - https://doi.org/10.1111/j.0909-752X.2006.00155.x DB - PRIME DP - Unbound Medicine ER -