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Types and rates of sequence evolution at the high-molecular-weight glutenin locus in hexaploid wheat and its ancestral genomes.
Genetics 2006; 174(3):1493-504G

Abstract

The Glu-1 locus, encoding the high-molecular-weight glutenin protein subunits, controls bread-making quality in hexaploid wheat (Triticum aestivum) and represents a recently evolved region unique to Triticeae genomes. To understand the molecular evolution of this locus region, three orthologous Glu-1 regions from the three subgenomes of a single hexaploid wheat species were sequenced, totaling 729 kb of sequence. Comparing each Glu-1 region with its corresponding homologous region from the D genome of diploid wheat, Aegilops tauschii, and the A and B genomes of tetraploid wheat, Triticum turgidum, revealed that, in addition to the conservation of microsynteny in the genic regions, sequences in the intergenic regions, composed of blocks of nested retroelements, are also generally conserved, although a few nonshared retroelements that differentiate the homologous Glu-1 regions were detected in each pair of the A and D genomes. Analysis of the indel frequency and the rate of nucleotide substitution, which represent the most frequent types of sequence changes in the Glu-1 regions, demonstrated that the two A genomes are significantly more divergent than the two B genomes, further supporting the hypothesis that hexaploid wheat may have more than one tetraploid ancestor.

Authors+Show Affiliations

United States Department of Agriculture-Agricultural Research Service, Western Regional Research Center, Albany, CA 94710, USA. ygu@pw.usda.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

17028342

Citation

Gu, Yong Qiang, et al. "Types and Rates of Sequence Evolution at the High-molecular-weight Glutenin Locus in Hexaploid Wheat and Its Ancestral Genomes." Genetics, vol. 174, no. 3, 2006, pp. 1493-504.
Gu YQ, Salse J, Coleman-Derr D, et al. Types and rates of sequence evolution at the high-molecular-weight glutenin locus in hexaploid wheat and its ancestral genomes. Genetics. 2006;174(3):1493-504.
Gu, Y. Q., Salse, J., Coleman-Derr, D., Dupin, A., Crossman, C., Lazo, G. R., ... Chalhoub, B. (2006). Types and rates of sequence evolution at the high-molecular-weight glutenin locus in hexaploid wheat and its ancestral genomes. Genetics, 174(3), pp. 1493-504.
Gu YQ, et al. Types and Rates of Sequence Evolution at the High-molecular-weight Glutenin Locus in Hexaploid Wheat and Its Ancestral Genomes. Genetics. 2006;174(3):1493-504. PubMed PMID: 17028342.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Types and rates of sequence evolution at the high-molecular-weight glutenin locus in hexaploid wheat and its ancestral genomes. AU - Gu,Yong Qiang, AU - Salse,Jérôme, AU - Coleman-Derr,Devin, AU - Dupin,Adeline, AU - Crossman,Curt, AU - Lazo,Gerard R, AU - Huo,Naxin, AU - Belcram,Harry, AU - Ravel,Catherine, AU - Charmet,Gilles, AU - Charles,Mathieu, AU - Anderson,Olin D, AU - Chalhoub,Boulos, Y1 - 2006/10/08/ PY - 2006/10/10/pubmed PY - 2007/2/1/medline PY - 2006/10/10/entrez SP - 1493 EP - 504 JF - Genetics JO - Genetics VL - 174 IS - 3 N2 - The Glu-1 locus, encoding the high-molecular-weight glutenin protein subunits, controls bread-making quality in hexaploid wheat (Triticum aestivum) and represents a recently evolved region unique to Triticeae genomes. To understand the molecular evolution of this locus region, three orthologous Glu-1 regions from the three subgenomes of a single hexaploid wheat species were sequenced, totaling 729 kb of sequence. Comparing each Glu-1 region with its corresponding homologous region from the D genome of diploid wheat, Aegilops tauschii, and the A and B genomes of tetraploid wheat, Triticum turgidum, revealed that, in addition to the conservation of microsynteny in the genic regions, sequences in the intergenic regions, composed of blocks of nested retroelements, are also generally conserved, although a few nonshared retroelements that differentiate the homologous Glu-1 regions were detected in each pair of the A and D genomes. Analysis of the indel frequency and the rate of nucleotide substitution, which represent the most frequent types of sequence changes in the Glu-1 regions, demonstrated that the two A genomes are significantly more divergent than the two B genomes, further supporting the hypothesis that hexaploid wheat may have more than one tetraploid ancestor. SN - 0016-6731 UR - https://www.unboundmedicine.com/medline/citation/17028342/Types_and_rates_of_sequence_evolution_at_the_high_molecular_weight_glutenin_locus_in_hexaploid_wheat_and_its_ancestral_genomes_ L2 - http://www.genetics.org/cgi/pmidlookup?view=long&pmid=17028342 DB - PRIME DP - Unbound Medicine ER -