Evaluation of tests for serological diagnosis of scrub typhus.Trop Doct. 2006 Oct; 36(4):212-3.TD
Abstract
Two specific serological tests, a Dot enzyme immunoassay (EIA) and an immunoglobulin (Ig)M enzyme-linked immunosorbent assay (ELISA) using the 56 kDa antigen and the Weil-Felix test were evaluated for diagnosis of scrub typhus. Sensitivity of 100, 86.5 and 43.5% were observed with Dot EIA, IgM ELISA and Weil-Felix test, respectively. False-positive reactions were observed in patients with falciparum malaria, pulmonary tuberculosis, S. viridans septicemia and typhoid fever using Dot EIA and IgM ELISA. Therefore, although Dot EIA and IgM ELISA are useful in the serodiagnosis of scrub typhus, efforts should be made to rule out other febrile illnesses.
Links
MeSH
Pub Type(s)
Evaluation Study
Journal Article
Language
eng
PubMed ID
17034691
Citation
Prakash, J A J., et al. "Evaluation of Tests for Serological Diagnosis of Scrub Typhus." Tropical Doctor, vol. 36, no. 4, 2006, pp. 212-3.
Prakash JA, Abraham OC, Mathai E. Evaluation of tests for serological diagnosis of scrub typhus. Trop Doct. 2006;36(4):212-3.
Prakash, J. A., Abraham, O. C., & Mathai, E. (2006). Evaluation of tests for serological diagnosis of scrub typhus. Tropical Doctor, 36(4), 212-3.
Prakash JA, Abraham OC, Mathai E. Evaluation of Tests for Serological Diagnosis of Scrub Typhus. Trop Doct. 2006;36(4):212-3. PubMed PMID: 17034691.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Evaluation of tests for serological diagnosis of scrub typhus.
AU - Prakash,J A J,
AU - Abraham,O C,
AU - Mathai,Elizabeth,
PY - 2006/10/13/pubmed
PY - 2006/12/12/medline
PY - 2006/10/13/entrez
SP - 212
EP - 3
JF - Tropical doctor
JO - Trop Doct
VL - 36
IS - 4
N2 - Two specific serological tests, a Dot enzyme immunoassay (EIA) and an immunoglobulin (Ig)M enzyme-linked immunosorbent assay (ELISA) using the 56 kDa antigen and the Weil-Felix test were evaluated for diagnosis of scrub typhus. Sensitivity of 100, 86.5 and 43.5% were observed with Dot EIA, IgM ELISA and Weil-Felix test, respectively. False-positive reactions were observed in patients with falciparum malaria, pulmonary tuberculosis, S. viridans septicemia and typhoid fever using Dot EIA and IgM ELISA. Therefore, although Dot EIA and IgM ELISA are useful in the serodiagnosis of scrub typhus, efforts should be made to rule out other febrile illnesses.
SN - 0049-4755
UR - https://www.unboundmedicine.com/medline/citation/17034691/Evaluation_of_tests_for_serological_diagnosis_of_scrub_typhus_
L2 - https://journals.sagepub.com/doi/10.1258/004947506778604715?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed
DB - PRIME
DP - Unbound Medicine
ER -