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[RP-HPLC fingerprint for quality assessment of Radix Angelicae dahuricae].
Yao Xue Xue Bao. 2006 Aug; 41(8):747-51.YX

Abstract

AIM

To establish the RP-HPLC fingerprint analysis for the quality control of Radix Angelicae dahuricae.

METHODS

HPLC fingerprint analysis method of Radix Angelicae dahuricae was developed. Kromasil C18 column (250 mm x 4.6 mm ID, 5 microm) was used, with mixture of acetonitrile and water as mobile phase in a gradient mode. The flow rate was 1.0 mL x min(-1). The wavelength of measurement was 254 nm. Twenty-one batches of Radix Angelicae dahuricae were determined.

RESULTS

The 21 samples were classified as 4 clusters by cluster analysis and the 11 superior in producing area samples were confirmed to establish the mutual model. The samples' quality was assessed by Similarity Evaluation System for Chromatographic Fingerprint of TCM 2004.

CONCLUSION

The method can be used to identify and evaluate the quality of Radix Angelicae dahuricae conveniently.

Authors+Show Affiliations

Wang TT
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Chen XH
No affiliation info available
Hu QQ
No affiliation info available
Bi KS
No affiliation info available

MeSH

AngelicaChromatography, High Pressure LiquidCluster AnalysisPlant ExtractsPlant RootsPlants, MedicinalQuality ControlReproducibility of Results

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

17039781

Citation

Wang, Ting-ting, et al. "[RP-HPLC Fingerprint for Quality Assessment of Radix Angelicae Dahuricae]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 41, no. 8, 2006, pp. 747-51.
Wang TT, Chen XH, Hu QQ, et al. [RP-HPLC fingerprint for quality assessment of Radix Angelicae dahuricae]. Yao Xue Xue Bao. 2006;41(8):747-51.
Wang, T. T., Chen, X. H., Hu, Q. Q., & Bi, K. S. (2006). [RP-HPLC fingerprint for quality assessment of Radix Angelicae dahuricae]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 41(8), 747-51.
Wang TT, et al. [RP-HPLC Fingerprint for Quality Assessment of Radix Angelicae Dahuricae]. Yao Xue Xue Bao. 2006;41(8):747-51. PubMed PMID: 17039781.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [RP-HPLC fingerprint for quality assessment of Radix Angelicae dahuricae]. AU - Wang,Ting-ting, AU - Chen,Xiao-hui, AU - Hu,Qing-qing, AU - Bi,Kai-shun, PY - 2006/10/17/pubmed PY - 2008/2/13/medline PY - 2006/10/17/entrez SP - 747 EP - 51 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 41 IS - 8 N2 - AIM: To establish the RP-HPLC fingerprint analysis for the quality control of Radix Angelicae dahuricae. METHODS: HPLC fingerprint analysis method of Radix Angelicae dahuricae was developed. Kromasil C18 column (250 mm x 4.6 mm ID, 5 microm) was used, with mixture of acetonitrile and water as mobile phase in a gradient mode. The flow rate was 1.0 mL x min(-1). The wavelength of measurement was 254 nm. Twenty-one batches of Radix Angelicae dahuricae were determined. RESULTS: The 21 samples were classified as 4 clusters by cluster analysis and the 11 superior in producing area samples were confirmed to establish the mutual model. The samples' quality was assessed by Similarity Evaluation System for Chromatographic Fingerprint of TCM 2004. CONCLUSION: The method can be used to identify and evaluate the quality of Radix Angelicae dahuricae conveniently. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/17039781/[RP_HPLC_fingerprint_for_quality_assessment_of_Radix_Angelicae_dahuricae]_ DB - PRIME DP - Unbound Medicine ER -