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Pneumocystis carinii pneumonia in patients with AIDS: evaluation of lavage and staining techniques in diagnosis.

Abstract

The diagnostic yield of unilateral vs. bilateral bronchoalveolar lavage (BAL) was prospectively evaluated in 65 consecutive patients suspected of having Pneumocystis carinii pneumonia (PCP) complicating acquired immune deficiency syndrome (AIDS). Gram-Weigert (GW), Papanicolaou (PAP), and Gomori's methenamine silver (GMS) stains were used for identification of P. carinii in all cases. Forty-eight patients had PCP that was identified by GW staining of BAL in 47/48 patients followed by PAP/GMS staining of BAL in 44/48 patients and PAP/GMS staining of bronchial washings in 40/48 patients. In patients with bilateral interstitial infiltrates, unilateral lavage was sufficient for diagnosis of PCP when GW stain was utilized. In patients with PCP complicating AIDS, the diagnostic yield of BAL may be increased by use of both GW and GMS stains.

Authors+Show Affiliations

Department of Medicine, State University of New York Health Science Center, Brooklyn.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

1704061

Citation

Chechani, V, et al. "Pneumocystis Carinii Pneumonia in Patients With AIDS: Evaluation of Lavage and Staining Techniques in Diagnosis." Journal of Acquired Immune Deficiency Syndromes, vol. 4, no. 3, 1991, pp. 250-3.
Chechani V, Allam AA, Haseeb MA, et al. Pneumocystis carinii pneumonia in patients with AIDS: evaluation of lavage and staining techniques in diagnosis. J Acquir Immune Defic Syndr (1988). 1991;4(3):250-3.
Chechani, V., Allam, A. A., Haseeb, M. A., & Kamholz, S. L. (1991). Pneumocystis carinii pneumonia in patients with AIDS: evaluation of lavage and staining techniques in diagnosis. Journal of Acquired Immune Deficiency Syndromes, 4(3), 250-3.
Chechani V, et al. Pneumocystis Carinii Pneumonia in Patients With AIDS: Evaluation of Lavage and Staining Techniques in Diagnosis. J Acquir Immune Defic Syndr (1988). 1991;4(3):250-3. PubMed PMID: 1704061.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pneumocystis carinii pneumonia in patients with AIDS: evaluation of lavage and staining techniques in diagnosis. AU - Chechani,V, AU - Allam,A A, AU - Haseeb,M A, AU - Kamholz,S L, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 250 EP - 3 JF - Journal of acquired immune deficiency syndromes JO - J Acquir Immune Defic Syndr (1988) VL - 4 IS - 3 N2 - The diagnostic yield of unilateral vs. bilateral bronchoalveolar lavage (BAL) was prospectively evaluated in 65 consecutive patients suspected of having Pneumocystis carinii pneumonia (PCP) complicating acquired immune deficiency syndrome (AIDS). Gram-Weigert (GW), Papanicolaou (PAP), and Gomori's methenamine silver (GMS) stains were used for identification of P. carinii in all cases. Forty-eight patients had PCP that was identified by GW staining of BAL in 47/48 patients followed by PAP/GMS staining of BAL in 44/48 patients and PAP/GMS staining of bronchial washings in 40/48 patients. In patients with bilateral interstitial infiltrates, unilateral lavage was sufficient for diagnosis of PCP when GW stain was utilized. In patients with PCP complicating AIDS, the diagnostic yield of BAL may be increased by use of both GW and GMS stains. SN - 0894-9255 UR - https://www.unboundmedicine.com/medline/citation/1704061/Pneumocystis_carinii_pneumonia_in_patients_with_AIDS:_evaluation_of_lavage_and_staining_techniques_in_diagnosis_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=1704061.ui DB - PRIME DP - Unbound Medicine ER -