Tags

Type your tag names separated by a space and hit enter

Pilot sample of very early onset bipolar disorder in a military population moderates the association of negative life events and non-fatal suicide attempt.
Bipolar Disord. 2006 Oct; 8(5 Pt 1):475-84.BD

Abstract

OBJECTIVE

To examine the moderating effects of very early onset diagnostic status (<or= 13 years) upon the association between life events and non-fatal suicide attempt.

METHODS

Measures of negative life events, suicidal ideation and current suicide attempt were administered to 298 military-based young adults at entry to treatment for suicidality. Current and lifetime diagnoses were assigned using the Diagnostic Interview Schedule. The predictive ability of negative life events for non-fatal suicide attempt was examined separately for the total sample and for those with retrospectively determined histories of very early onset bipolar disorder (VEOBPD; n = 16), very early onset major depressive disorder (VEOMDD; n = 21) and very early onset anxiety disorder (VEOANX; n = 53).

RESULTS

Negative life events and suicide attempt were significantly and positively associated among those with no history of VEOBPD (OR = 1.30, 95% CI = 1.02-1.65, p < 0.05), including those with VEOMDD and VEOANX. Consistent with expectation, VEOBPD moderated the association between negative life events and suicide attempt (OR = 0.88, 95% CI = 0.78-0.99, p < 0.05), such that negative life events were non-significantly and negatively associated with the presence of a suicide attempt (OR = 0.21, 95% CI = 0.04-1.02, p = 0.09) among patients with a history of VEOBPD.

CONCLUSIONS

Despite similar rates of suicide attempt among all diagnostic groups, life stress did not contribute to attempt among those with VEOBPD. These findings are consistent with the severity and chronicity of VEOBPD. Potential explanations of these findings include a scarring effect on coping skills and increased sensitization to life stress.

Authors+Show Affiliations

Department of Psychology, University of Houston, Houston, TX 77204-5022, USA. jpettit@uh.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17042885

Citation

Pettit, Jeremy W., et al. "Pilot Sample of Very Early Onset Bipolar Disorder in a Military Population Moderates the Association of Negative Life Events and Non-fatal Suicide Attempt." Bipolar Disorders, vol. 8, no. 5 Pt 1, 2006, pp. 475-84.
Pettit JW, Paukert AL, Joiner TE, et al. Pilot sample of very early onset bipolar disorder in a military population moderates the association of negative life events and non-fatal suicide attempt. Bipolar Disord. 2006;8(5 Pt 1):475-84.
Pettit, J. W., Paukert, A. L., Joiner, T. E., & Rudd, M. D. (2006). Pilot sample of very early onset bipolar disorder in a military population moderates the association of negative life events and non-fatal suicide attempt. Bipolar Disorders, 8(5 Pt 1), 475-84.
Pettit JW, et al. Pilot Sample of Very Early Onset Bipolar Disorder in a Military Population Moderates the Association of Negative Life Events and Non-fatal Suicide Attempt. Bipolar Disord. 2006;8(5 Pt 1):475-84. PubMed PMID: 17042885.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pilot sample of very early onset bipolar disorder in a military population moderates the association of negative life events and non-fatal suicide attempt. AU - Pettit,Jeremy W, AU - Paukert,Amber L, AU - Joiner,Thomas E,Jr AU - Rudd,M David, PY - 2006/10/18/pubmed PY - 2007/3/3/medline PY - 2006/10/18/entrez SP - 475 EP - 84 JF - Bipolar disorders JO - Bipolar Disord VL - 8 IS - 5 Pt 1 N2 - OBJECTIVE: To examine the moderating effects of very early onset diagnostic status (<or= 13 years) upon the association between life events and non-fatal suicide attempt. METHODS: Measures of negative life events, suicidal ideation and current suicide attempt were administered to 298 military-based young adults at entry to treatment for suicidality. Current and lifetime diagnoses were assigned using the Diagnostic Interview Schedule. The predictive ability of negative life events for non-fatal suicide attempt was examined separately for the total sample and for those with retrospectively determined histories of very early onset bipolar disorder (VEOBPD; n = 16), very early onset major depressive disorder (VEOMDD; n = 21) and very early onset anxiety disorder (VEOANX; n = 53). RESULTS: Negative life events and suicide attempt were significantly and positively associated among those with no history of VEOBPD (OR = 1.30, 95% CI = 1.02-1.65, p < 0.05), including those with VEOMDD and VEOANX. Consistent with expectation, VEOBPD moderated the association between negative life events and suicide attempt (OR = 0.88, 95% CI = 0.78-0.99, p < 0.05), such that negative life events were non-significantly and negatively associated with the presence of a suicide attempt (OR = 0.21, 95% CI = 0.04-1.02, p = 0.09) among patients with a history of VEOBPD. CONCLUSIONS: Despite similar rates of suicide attempt among all diagnostic groups, life stress did not contribute to attempt among those with VEOBPD. These findings are consistent with the severity and chronicity of VEOBPD. Potential explanations of these findings include a scarring effect on coping skills and increased sensitization to life stress. SN - 1398-5647 UR - https://www.unboundmedicine.com/medline/citation/17042885/Pilot_sample_of_very_early_onset_bipolar_disorder_in_a_military_population_moderates_the_association_of_negative_life_events_and_non_fatal_suicide_attempt_ DB - PRIME DP - Unbound Medicine ER -